The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski; Edik U. Rafailov

doi:10.1117/12.2212758

The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

Victor V. Dremin, Victor V. Sidorov, Alexander I. Krupatkin, Gagik R. Galstyan, Irina N. Novikova, Angelina I. Zherebtsova, Evgeny A. Zherebtsov, Andrey V. Dunaev, Zera N. Abdulvapova, Karina S. Litvinova, Ilya E. Rafailov, Sergei G. Sokolovski, Edik U. Rafailov

Research output: Chapter in Book/Published conference output › Conference publication

Abstract

Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

Original language	English
Title of host publication	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Editors	Tuan Vo-Dinh, Anita Mahadevan-Jansen, Warren S. Grundfest
Place of Publication	Bellingham, WA (US)
Publisher	SPIE
Number of pages	7
ISBN (Print)	978-1-6284-1932-0
DOIs	https://doi.org/10.1117/12.2212758
Publication status	Published - 7 Mar 2016
Event	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV - San Francisco, United States Duration: 14 Feb 2016 → 16 Feb 2016

Publication series

Name	SPIE Proceedings
Publisher	SPIE
Volume	9698
ISSN (Print)	0277-786X
ISSN (Electronic)	2410-9045

Conference

Conference	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
Country/Territory	United States
City	San Francisco
Period	14/02/16 → 16/02/16

Bibliographical note

Copyright © 2016. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Keywords

diabetic foot syndrome
fluorescence spectroscopy
laser Doppler flowmetry
microcirculation
redox ratio

Access to Document

10.1117/12.2212758

Blood perfusion and NADH_FAD content combined analysis
Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski and Edik U. Rafailov; "The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot", Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 969810 (March 7, 2016). Copyright 2016. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. DOI: http://dx.doi.org/10.1117/12.2212758
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Cite this

Dremin, V. V., Sidorov, V. V., Krupatkin, A. I., Galstyan, G. R., Novikova, I. N., Zherebtsova, A. I., Zherebtsov, E. A., Dunaev, A. V., Abdulvapova, Z. N., Litvinova, K. S., Rafailov, I. E., Sokolovski, S. G., & Rafailov, E. U. (2016). The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. In T. Vo-Dinh, A. Mahadevan-Jansen, & W. S. Grundfest (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE Article 969810 (SPIE Proceedings; Vol. 9698). SPIE. https://doi.org/10.1117/12.2212758

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title = "The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot",

abstract = "Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.",

keywords = "diabetic foot syndrome, fluorescence spectroscopy, laser Doppler flowmetry, microcirculation, redox ratio",

author = "Dremin, {Victor V.} and Sidorov, {Victor V.} and Krupatkin, {Alexander I.} and Galstyan, {Gagik R.} and Novikova, {Irina N.} and Zherebtsova, {Angelina I.} and Zherebtsov, {Evgeny A.} and Dunaev, {Andrey V.} and Abdulvapova, {Zera N.} and Litvinova, {Karina S.} and Rafailov, {Ilya E.} and Sokolovski, {Sergei G.} and Rafailov, {Edik U.}",

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Dremin, VV, Sidorov, VV, Krupatkin, AI, Galstyan, GR, Novikova, IN, Zherebtsova, AI, Zherebtsov, EA, Dunaev, AV, Abdulvapova, ZN, Litvinova, KS, Rafailov, IE, Sokolovski, SG & Rafailov, EU 2016, The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. in T Vo-Dinh, A Mahadevan-Jansen & WS Grundfest (eds), Progress in Biomedical Optics and Imaging - Proceedings of SPIE., 969810, SPIE Proceedings, vol. 9698, SPIE, Bellingham, WA (US), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, San Francisco, United States, 14/02/16. https://doi.org/10.1117/12.2212758

The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. / Dremin, Victor V.; Sidorov, Victor V.; Krupatkin, Alexander I. et al.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. ed. / Tuan Vo-Dinh; Anita Mahadevan-Jansen; Warren S. Grundfest. Bellingham, WA (US): SPIE, 2016. 969810 (SPIE Proceedings; Vol. 9698).

Research output: Chapter in Book/Published conference output › Conference publication

TY - GEN

T1 - The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

AU - Dremin, Victor V.

AU - Sidorov, Victor V.

AU - Krupatkin, Alexander I.

AU - Galstyan, Gagik R.

AU - Novikova, Irina N.

AU - Zherebtsova, Angelina I.

AU - Zherebtsov, Evgeny A.

AU - Dunaev, Andrey V.

AU - Abdulvapova, Zera N.

AU - Litvinova, Karina S.

AU - Rafailov, Ilya E.

AU - Sokolovski, Sergei G.

AU - Rafailov, Edik U.

N1 - Copyright © 2016. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

PY - 2016/3/7

Y1 - 2016/3/7

N2 - Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

AB - Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

KW - diabetic foot syndrome

KW - fluorescence spectroscopy

KW - laser Doppler flowmetry

KW - microcirculation

KW - redox ratio

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SN - 978-1-6284-1932-0

T3 - SPIE Proceedings

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

A2 - Vo-Dinh, Tuan

A2 - Mahadevan-Jansen, Anita

A2 - Grundfest, Warren S.

PB - SPIE

CY - Bellingham, WA (US)

T2 - Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV

Y2 - 14 February 2016 through 16 February 2016

ER -

Dremin VV, Sidorov VV, Krupatkin AI, Galstyan GR, Novikova IN, Zherebtsova AI et al. The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. In Vo-Dinh T, Mahadevan-Jansen A, Grundfest WS, editors, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Bellingham, WA (US): SPIE. 2016. 969810. (SPIE Proceedings). doi: 10.1117/12.2212758

The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

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Keywords

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