Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.
|Title of host publication||Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV|
|Editors||Tuan Vo-Dinh, Anita Mahadevan-Jansen, Warren S. Grundfest|
|Place of Publication||Bellingham, WA (US)|
|Number of pages||7|
|Publication status||Published - 7 Mar 2016|
|Event||Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV - San Francisco, United States|
Duration: 14 Feb 2016 → 16 Feb 2016
|Name||Progress in Biomedical Optics and Imaging|
|Conference||Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV|
|Period||14/02/16 → 16/02/16|
Bibliographical noteVictor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski and Edik U. Rafailov; "The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot", Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 969810 (March 7, 2016).
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- diabetic foot syndrome
- fluorescence spectroscopy
- laser Doppler flowmetry
- redox ratio