The electroretinogram: a useful tool for evaluating age-related macular disease?

Emma J Berrow, Hannah Bartlett Eperjesi, Frank Eperjesi, Jonathan Gibson

Research output: Contribution to journalArticlepeer-review


With an ageing population, the number of age-related macular disease (ARMD) cases will inevitably rise. This gives greater impetus for the need to identify the disease earlier and assess treatments to slow disease progression. Differing electroretinogram (ERG) modalities have been reviewed in relation to the objective assessment of retinal function in ARMD and for monitoring the effectiveness of clinical interventions. Conflicting results have been found with regard to the efficacy of ERG findings in the investigation of ARMD in previous years. The newer multifocal ERG paradigm provides spatial topographical information about retinal function in ARMD. It has shown promising results in monitoring effectiveness of clinical interventions and studies are continuing in this area. Better knowledge of retinal function in ARMD may lead to enhanced treatments at each phase of the disease.
Original languageEnglish
Pages (from-to)51-62
Number of pages12
JournalDocumenta Ophthalmologica
Issue number1
Early online date16 Mar 2010
Publication statusPublished - Aug 2010

Bibliographical note

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  • disease progression
  • electroretinography
  • humans
  • macular degeneration
  • population surveillance
  • retina
  • treatment outcome


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