Abstract
With an ageing population, the number of age-related macular disease (ARMD) cases will inevitably rise. This gives greater impetus for the need to identify the disease earlier and assess treatments to slow disease progression. Differing electroretinogram (ERG) modalities have been reviewed in relation to the objective assessment of retinal function in ARMD and for monitoring the effectiveness of clinical interventions. Conflicting results have been found with regard to the efficacy of ERG findings in the investigation of ARMD in previous years. The newer multifocal ERG paradigm provides spatial topographical information about retinal function in ARMD. It has shown promising results in monitoring effectiveness of clinical interventions and studies are continuing in this area. Better knowledge of retinal function in ARMD may lead to enhanced treatments at each phase of the disease.
Original language | English |
---|---|
Pages (from-to) | 51-62 |
Number of pages | 12 |
Journal | Documenta Ophthalmologica |
Volume | 121 |
Issue number | 1 |
Early online date | 16 Mar 2010 |
DOIs | |
Publication status | Published - Aug 2010 |
Bibliographical note
The original publication is available at www.springerlink.comKeywords
- disease progression
- electroretinography
- humans
- macular degeneration
- population surveillance
- retina
- treatment outcome