The first experience in estimation of basal cell carcinoma cryoresistence using noninvasive spectrophotometry

V. V. Andrukhina; K. S. Litvinova; A. A. Nikitin; N. Z. Spiridonova; D. A. Rogatkin

doi:10.1117/12.855086

The first experience in estimation of basal cell carcinoma cryoresistence using noninvasive spectrophotometry

V. V. Andrukhina, K. S. Litvinova, A. A. Nikitin, N. Z. Spiridonova, D. A. Rogatkin

Aston Medical School

Research output: Contribution to journal › Conference article › peer-review

Abstract

The urgency of BCC study affecting maxillofacial area and neck is not only caused by high prevalence of this disease, but also insufficient efficiency of existing treatment methods which lead to full or partial recovery only in 60-80% of cases. We analyzed the results of 198 BCC cases cryosurgical treatment. 33 (16,6%) patients showed continued tumor growth. It has been hypothesized that the behavior and character of microcirculation changes during patient's testing have to correlate with damaging rate of tumors that will allow to develop indications for surgical treatment with local destruction - cryosurgery or cryolaser treatment. We have tested the new group of 33 patients with primary and recurrence types of basal cell carcinoma (BCC) by means of Laser Doppler Flowmetry, Tissues Reflectance Oximetry, Laser Fluorescence Diagnostics before operation. It was shown that the microcirculatory data indicates the presence of cryoresistance.

Original language	English
Article number	75470G
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	7547
DOIs	https://doi.org/10.1117/12.855086
Publication status	Published - 11 Feb 2010
Event	Saratov Fall Meeting 2009 - International School for Junior Scientists and Students on Optics, Laser Physics, and Biophotonics - Saratov, Russian Federation Duration: 21 Sept 2009 → 24 Sept 2009

Keywords

BCC
Cryosurgery
In vivo
Laser Doppler Flowmetry
Noninvasive
Spectrophotometry

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10.1117/12.855086

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title = "The first experience in estimation of basal cell carcinoma cryoresistence using noninvasive spectrophotometry",

abstract = "The urgency of BCC study affecting maxillofacial area and neck is not only caused by high prevalence of this disease, but also insufficient efficiency of existing treatment methods which lead to full or partial recovery only in 60-80% of cases. We analyzed the results of 198 BCC cases cryosurgical treatment. 33 (16,6%) patients showed continued tumor growth. It has been hypothesized that the behavior and character of microcirculation changes during patient's testing have to correlate with damaging rate of tumors that will allow to develop indications for surgical treatment with local destruction - cryosurgery or cryolaser treatment. We have tested the new group of 33 patients with primary and recurrence types of basal cell carcinoma (BCC) by means of Laser Doppler Flowmetry, Tissues Reflectance Oximetry, Laser Fluorescence Diagnostics before operation. It was shown that the microcirculatory data indicates the presence of cryoresistance.",

keywords = "BCC, Cryosurgery, In vivo, Laser Doppler Flowmetry, Noninvasive, Spectrophotometry",

author = "Andrukhina, {V. V.} and Litvinova, {K. S.} and Nikitin, {A. A.} and Spiridonova, {N. Z.} and Rogatkin, {D. A.}",

year = "2010",

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T1 - The first experience in estimation of basal cell carcinoma cryoresistence using noninvasive spectrophotometry

AU - Andrukhina, V. V.

AU - Litvinova, K. S.

AU - Nikitin, A. A.

AU - Spiridonova, N. Z.

AU - Rogatkin, D. A.

PY - 2010/2/11

Y1 - 2010/2/11

N2 - The urgency of BCC study affecting maxillofacial area and neck is not only caused by high prevalence of this disease, but also insufficient efficiency of existing treatment methods which lead to full or partial recovery only in 60-80% of cases. We analyzed the results of 198 BCC cases cryosurgical treatment. 33 (16,6%) patients showed continued tumor growth. It has been hypothesized that the behavior and character of microcirculation changes during patient's testing have to correlate with damaging rate of tumors that will allow to develop indications for surgical treatment with local destruction - cryosurgery or cryolaser treatment. We have tested the new group of 33 patients with primary and recurrence types of basal cell carcinoma (BCC) by means of Laser Doppler Flowmetry, Tissues Reflectance Oximetry, Laser Fluorescence Diagnostics before operation. It was shown that the microcirculatory data indicates the presence of cryoresistance.

AB - The urgency of BCC study affecting maxillofacial area and neck is not only caused by high prevalence of this disease, but also insufficient efficiency of existing treatment methods which lead to full or partial recovery only in 60-80% of cases. We analyzed the results of 198 BCC cases cryosurgical treatment. 33 (16,6%) patients showed continued tumor growth. It has been hypothesized that the behavior and character of microcirculation changes during patient's testing have to correlate with damaging rate of tumors that will allow to develop indications for surgical treatment with local destruction - cryosurgery or cryolaser treatment. We have tested the new group of 33 patients with primary and recurrence types of basal cell carcinoma (BCC) by means of Laser Doppler Flowmetry, Tissues Reflectance Oximetry, Laser Fluorescence Diagnostics before operation. It was shown that the microcirculatory data indicates the presence of cryoresistance.

KW - BCC

KW - Cryosurgery

KW - In vivo

KW - Laser Doppler Flowmetry

KW - Noninvasive

KW - Spectrophotometry

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DO - 10.1117/12.855086

M3 - Conference article

AN - SCOPUS:77953258386

SN - 0277-786X

VL - 7547

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

M1 - 75470G

T2 - Saratov Fall Meeting 2009 - International School for Junior Scientists and Students on Optics, Laser Physics, and Biophotonics

Y2 - 21 September 2009 through 24 September 2009

ER -

The first experience in estimation of basal cell carcinoma cryoresistence using noninvasive spectrophotometry

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