The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence

E. A. Zherebtsov*, K. Y. Kandurova, E. S. Seryogina, I. O. Kozlov, V. V. Dremin, A. I. Zherebtsova, A. V. Dunaev, I. Meglinski

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


This article presents the results of the study of the pressure applied on optical diagnostic probes as a significant factor affecting the results of measurements. During stepwise increasing and decreasing of local pressure on skin we conducted measurements using the methods of laser Doppler flowmetry and fluorescence spectroscopy. It was found out that pressure on optical probe has sufficient impact on skin microcirculation to affect registered fluorescence intensity. Data obtained in this study are of interest for design and development of diagnostic technologies for wearable devices. This data will also inform further investigation into issues of compensation of blood absorption influence on fluorescence spectrum, allowing increased accuracy and reproducibility of measurements by fluorescence spectroscopy methods in optical diagnosis.

Original languageEnglish
Article number1033608
JournalProceedings of SPIE - International Society for Optical Engineering
Publication statusPublished - 24 Mar 2017
Event4th International Symposium on Optics and Biophotonics, SFM 2016 - Saratov, Russian Federation
Duration: 27 Sept 201630 Sept 2016

Bibliographical note

Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.


  • Blood microcirculation
  • Fluorescence spectroscopy
  • Laser Doppler flowmetry
  • Local pressure
  • Non-invasive diagnostics
  • Wearable technology


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