The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence

E. A. Zherebtsov; K. Y. Kandurova; E. S. Seryogina; I. O. Kozlov; V. V. Dremin; A. I. Zherebtsova; A. V. Dunaev; I. Meglinski

doi:10.1117/12.2267957

The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence

E. A. Zherebtsov^*, K. Y. Kandurova, E. S. Seryogina, I. O. Kozlov, V. V. Dremin, A. I. Zherebtsova, A. V. Dunaev, I. Meglinski

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

Abstract

This article presents the results of the study of the pressure applied on optical diagnostic probes as a significant factor affecting the results of measurements. During stepwise increasing and decreasing of local pressure on skin we conducted measurements using the methods of laser Doppler flowmetry and fluorescence spectroscopy. It was found out that pressure on optical probe has sufficient impact on skin microcirculation to affect registered fluorescence intensity. Data obtained in this study are of interest for design and development of diagnostic technologies for wearable devices. This data will also inform further investigation into issues of compensation of blood absorption influence on fluorescence spectrum, allowing increased accuracy and reproducibility of measurements by fluorescence spectroscopy methods in optical diagnosis.

Original language	English
Article number	1033608
Journal	Proceedings of SPIE - International Society for Optical Engineering
Volume	10336
DOIs	https://doi.org/10.1117/12.2267957
Publication status	Published - 24 Mar 2017
Event	4th International Symposium on Optics and Biophotonics, SFM 2016 - Saratov, Russian Federation Duration: 27 Sept 2016 → 30 Sept 2016

Bibliographical note

Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Keywords

Blood microcirculation
Fluorescence spectroscopy
Laser Doppler flowmetry
Local pressure
Non-invasive diagnostics
Wearable technology

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title = "The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence",

abstract = "This article presents the results of the study of the pressure applied on optical diagnostic probes as a significant factor affecting the results of measurements. During stepwise increasing and decreasing of local pressure on skin we conducted measurements using the methods of laser Doppler flowmetry and fluorescence spectroscopy. It was found out that pressure on optical probe has sufficient impact on skin microcirculation to affect registered fluorescence intensity. Data obtained in this study are of interest for design and development of diagnostic technologies for wearable devices. This data will also inform further investigation into issues of compensation of blood absorption influence on fluorescence spectrum, allowing increased accuracy and reproducibility of measurements by fluorescence spectroscopy methods in optical diagnosis.",

keywords = "Blood microcirculation, Fluorescence spectroscopy, Laser Doppler flowmetry, Local pressure, Non-invasive diagnostics, Wearable technology",

author = "Zherebtsov, {E. A.} and Kandurova, {K. Y.} and Seryogina, {E. S.} and Kozlov, {I. O.} and Dremin, {V. V.} and Zherebtsova, {A. I.} and Dunaev, {A. V.} and I. Meglinski",

note = "Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. ; 4th International Symposium on Optics and Biophotonics, SFM 2016 ; Conference date: 27-09-2016 Through 30-09-2016",

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T1 - The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence

AU - Zherebtsov, E. A.

AU - Kandurova, K. Y.

AU - Seryogina, E. S.

AU - Kozlov, I. O.

AU - Dremin, V. V.

AU - Zherebtsova, A. I.

AU - Dunaev, A. V.

AU - Meglinski, I.

N1 - Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

PY - 2017/3/24

Y1 - 2017/3/24

N2 - This article presents the results of the study of the pressure applied on optical diagnostic probes as a significant factor affecting the results of measurements. During stepwise increasing and decreasing of local pressure on skin we conducted measurements using the methods of laser Doppler flowmetry and fluorescence spectroscopy. It was found out that pressure on optical probe has sufficient impact on skin microcirculation to affect registered fluorescence intensity. Data obtained in this study are of interest for design and development of diagnostic technologies for wearable devices. This data will also inform further investigation into issues of compensation of blood absorption influence on fluorescence spectrum, allowing increased accuracy and reproducibility of measurements by fluorescence spectroscopy methods in optical diagnosis.

AB - This article presents the results of the study of the pressure applied on optical diagnostic probes as a significant factor affecting the results of measurements. During stepwise increasing and decreasing of local pressure on skin we conducted measurements using the methods of laser Doppler flowmetry and fluorescence spectroscopy. It was found out that pressure on optical probe has sufficient impact on skin microcirculation to affect registered fluorescence intensity. Data obtained in this study are of interest for design and development of diagnostic technologies for wearable devices. This data will also inform further investigation into issues of compensation of blood absorption influence on fluorescence spectrum, allowing increased accuracy and reproducibility of measurements by fluorescence spectroscopy methods in optical diagnosis.

KW - Blood microcirculation

KW - Fluorescence spectroscopy

KW - Laser Doppler flowmetry

KW - Local pressure

KW - Non-invasive diagnostics

KW - Wearable technology

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UR - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10336/1/The-influence-of-local-pressure-on-evaluation-parameters-of-skin/10.1117/12.2267957.full

U2 - 10.1117/12.2267957

DO - 10.1117/12.2267957

M3 - Conference article

AN - SCOPUS:85019222718

SN - 0277-786X

VL - 10336

JO - Proceedings of SPIE - International Society for Optical Engineering

JF - Proceedings of SPIE - International Society for Optical Engineering

M1 - 1033608

T2 - 4th International Symposium on Optics and Biophotonics, SFM 2016

Y2 - 27 September 2016 through 30 September 2016

ER -

The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence

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Keywords

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