TY - UNPB
T1 - The Kyphosis-lordosis Difference Parameter and Its Utility in Understanding the Pathogenesis of Adolescent Idiopathic Scoliosis
AU - Gardner, Adrian
AU - Berryman, Fiona
AU - Pynsent, Paul
PY - 2022/2/23
Y1 - 2022/2/23
N2 - Objective: The relationship of sagittal spinal shape in the pathogenesis of adolescent idiopathic scoliosis (AIS) is recognised. What is not clear is the relationship between the sagittal shape of those without scoliosis and the potential development of AIS, including the greater prevalence in females. The use of a new parameter, the kyphosis-lordosis (KL) difference, was developed to explore this further.Results:The KL difference was calculated for 117 males and 79 females over seven years with 831 measures made. For females, the KL difference, between the ages of 9 and 12 ½ years, decreases from 5° to nearly 0° until starting to climb again from the age of 14 years, back to 5° by the age of 16 ½ years. For males, there is a gradual decline from 9° at age 9 years to 5° at age 17 years. Both age and sex were statistically significant in the development of the parameter. When comparing to previously published data around the true, de-rotated, sagittal shape of the scoliotic spine, the KL difference has utility in explaining the female predominance in the prevalence of AIS. This adds to the weight of evidence behind understanding why AIS develops.
AB - Objective: The relationship of sagittal spinal shape in the pathogenesis of adolescent idiopathic scoliosis (AIS) is recognised. What is not clear is the relationship between the sagittal shape of those without scoliosis and the potential development of AIS, including the greater prevalence in females. The use of a new parameter, the kyphosis-lordosis (KL) difference, was developed to explore this further.Results:The KL difference was calculated for 117 males and 79 females over seven years with 831 measures made. For females, the KL difference, between the ages of 9 and 12 ½ years, decreases from 5° to nearly 0° until starting to climb again from the age of 14 years, back to 5° by the age of 16 ½ years. For males, there is a gradual decline from 9° at age 9 years to 5° at age 17 years. Both age and sex were statistically significant in the development of the parameter. When comparing to previously published data around the true, de-rotated, sagittal shape of the scoliotic spine, the KL difference has utility in explaining the female predominance in the prevalence of AIS. This adds to the weight of evidence behind understanding why AIS develops.
UR - https://www.researchsquare.com/article/rs-1155667/v1
U2 - 10.21203/rs.3.rs-1155667/v1
DO - 10.21203/rs.3.rs-1155667/v1
M3 - Preprint
BT - The Kyphosis-lordosis Difference Parameter and Its Utility in Understanding the Pathogenesis of Adolescent Idiopathic Scoliosis
ER -