The manufacture and preliminary testing of a novel Bio-MEMS filtration chip

P. T. Docker*, M. Prince, P. K. Kinnell, M. C L Ward, X. Ma

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In the clinical/microbiological laboratory there are currently several ways of separating specific cells from a fluid suspension. Conventionally cells can be separated based on size, density, electrical charge, light-scattering properties, and antigenic surface properties. Separating cells using these parameters can require complex technologies and specialist equipment which may damage sensitive cells. The pumping mechanism described here leaves samples undamaged either mechanically or chemically unlike many other current filtration techniques. This paper proposes new Bio-MEMS filtration chips manufactured using micro systems technology (MST) that, when used in conjunction with an optical microscope and a syringe, can filter and grade cells for size without the requirement for additional expensive equipment. These chips also offer great versatility in terms of design and their low cost allows them to be disposable, eliminating sample contamination.

Original languageEnglish
Title of host publication2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings
EditorsM. Laudon, B. Romanowicz
Pages692-695
Number of pages4
Publication statusPublished - 1 Dec 2005
Event2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 - Anaheim, CA, United Kingdom
Duration: 8 May 200512 May 2005

Conference

Conference2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005
CountryUnited Kingdom
CityAnaheim, CA
Period8/05/0512/05/05

Keywords

  • Bio mems
  • DRIE
  • Filters

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    Docker, P. T., Prince, M., Kinnell, P. K., Ward, M. C. L., & Ma, X. (2005). The manufacture and preliminary testing of a novel Bio-MEMS filtration chip. In M. Laudon, & B. Romanowicz (Eds.), 2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings (pp. 692-695)