The missing link: Analogous human and primate cortical gamma oscillations

Stephen D. Hall*, Ian E. Holliday, Arjan Hillebrand, Krish D. Singh, Paul L. Furlong, Avgis Hadjipapas, Gareth R. Barnes

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Recent animal studies highlighting the relationship between functional imaging signals and the underlying neuronal activity have revealed the potential capabilities of non-invasive methods. However, the valuable exchange of information between animal and human studies remains restricted by the limited evidence of direct physiological links between species. In this study we used magnetoencephalography (MEG) to investigate the occurrence of 30-70 Hz (gamma) oscillations in human visual cortex, induced by the presentation of visual stimuli of varying contrast. These oscillations, well described in the animal literature, were observed in retinotopically concordant locations of visual cortex and show striking similarity to those found in primate visual cortex using surgically implanted electrodes. The amplitude of the gamma oscillations increases linearly with stimulus contrast in strong correlation with the gamma oscillations found in the local field potential (LFP) of the macaque. We demonstrate that non-invasive magnetic field measurements of gamma oscillations in human visual cortex concur with invasive measures of activation in primate visual cortex, suggesting both a direct representation of underlying neuronal activity and a concurrence between human and primate cortical activity. © 2005 Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)13-17
Number of pages5
JournalNeuroimage
Volume26
Issue number1
DOIs
Publication statusPublished - 15 May 2005

Keywords

  • contrast
  • gamma
  • magnetoencephalography (MEG)
  • primary visual cortex
  • synthetic aperture magnetometry (SAM)

Fingerprint Dive into the research topics of 'The missing link: Analogous human and primate cortical gamma oscillations'. Together they form a unique fingerprint.

  • Cite this

    Hall, S. D., Holliday, I. E., Hillebrand, A., Singh, K. D., Furlong, P. L., Hadjipapas, A., & Barnes, G. R. (2005). The missing link: Analogous human and primate cortical gamma oscillations. Neuroimage, 26(1), 13-17. https://doi.org/10.1016/j.neuroimage.2005.01.009