TY - JOUR
T1 - The PRINTS database of protein fingerprints
T2 - a novel information resource for computational molecular biology
AU - Attwood, T.K.
AU - Avison, H.
AU - Beck, M.E.
AU - Bewley, M.
AU - Bleasby, A.J.
AU - Brewster, F.
AU - Cooper, P.
AU - Degtyarenko, K.
AU - Geddes, A.J.
AU - Flower, D.R.
AU - Kelly, M.P.
AU - Lott, S.
AU - Measures, K.M.
AU - Parry-Smith, D.J.
AU - Perkins, D.N.
AU - Scordis, P.
AU - Scott, D.
AU - Worledge, C.
PY - 1997/5
Y1 - 1997/5
N2 - PRINTS is a compendium of protein motif fingerprints derived from the OWL composite sequence database. Fingerprints are groups of motifs within sequence alignments whose conserved nature allows them to be used as signatures of family membership. Fingerprints inherently offer improved diagnostic reliability over single motif methods by virtue of the mutual context provided by motif neighbors. To date, 650 fingerprints have been constructed and stored in PRINTS, the size of which has doubled in the last 2 years. The current version, 14.0, encodes 3500 motifs, covering a range of globular and membrane proteins, modular polypeptides, and so on. The database is now accessible via the UCL Bioinformatics Server on http://www.biochem.ucl.ac.uk/bsm/dbbrowser/. We describe here progress with the database, its compilation and interrogation software, and its Web interface
AB - PRINTS is a compendium of protein motif fingerprints derived from the OWL composite sequence database. Fingerprints are groups of motifs within sequence alignments whose conserved nature allows them to be used as signatures of family membership. Fingerprints inherently offer improved diagnostic reliability over single motif methods by virtue of the mutual context provided by motif neighbors. To date, 650 fingerprints have been constructed and stored in PRINTS, the size of which has doubled in the last 2 years. The current version, 14.0, encodes 3500 motifs, covering a range of globular and membrane proteins, modular polypeptides, and so on. The database is now accessible via the UCL Bioinformatics Server on http://www.biochem.ucl.ac.uk/bsm/dbbrowser/. We describe here progress with the database, its compilation and interrogation software, and its Web interface
UR - http://pubs.acs.org/doi/abs/10.1021/ci960468e
U2 - 10.1021/ci960468e
DO - 10.1021/ci960468e
M3 - Article
SN - 0095-2338
VL - 37
SP - 417
EP - 424
JO - Journal of Chemical Information and Computer Sciences
JF - Journal of Chemical Information and Computer Sciences
IS - 3
ER -