TY - JOUR
T1 - The rational design of vaccines
AU - Bramwell, Vincent W.
AU - Perrie, Yvonne
PY - 2005/11/15
Y1 - 2005/11/15
N2 - This review provides an insight into the various opportunities for vaccine intervention, analysis of strategies for vaccine development, vaccine ability to modulate immune responses and resultant rational vaccine design. In addition, wider aspects are considered, such as biotechnological advances, advances in immunological understanding and host-pathogen interactions. The key question addressed here is, with all our research and understanding, have we reached a new echelon in vaccine development, that of rational design? ©2005 Elsevier Ltd. All rights reserved.
AB - This review provides an insight into the various opportunities for vaccine intervention, analysis of strategies for vaccine development, vaccine ability to modulate immune responses and resultant rational vaccine design. In addition, wider aspects are considered, such as biotechnological advances, advances in immunological understanding and host-pathogen interactions. The key question addressed here is, with all our research and understanding, have we reached a new echelon in vaccine development, that of rational design? ©2005 Elsevier Ltd. All rights reserved.
KW - pharmaceutical science
KW - drug discovery
KW - immunology
KW - biotechnology
UR - http://www.scopus.com/inward/record.url?scp=27344445179&partnerID=8YFLogxK
UR - https://www.sciencedirect.com/science/article/pii/S1359644605036007?via%3Dihub
U2 - 10.1016/S1359-6446(05)03600-7
DO - 10.1016/S1359-6446(05)03600-7
M3 - Article
C2 - 16257375
SN - 1359-6446
VL - 10
SP - 1527
EP - 1534
JO - Drug Discovery Today
JF - Drug Discovery Today
IS - 22
ER -