The relationship between alexithymia and salivary cortisol levels in somatoform disorders

Francisco Pedrosa Gil, Martin Bidlingmaier, Nathan Ridout, Carl Eduard Scheidt, Samantha Caton, Claudia Schoechlin, Marius Nickel

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Abstract

The purpose of this study was to investigate cortisol levels as a function of the hypothalamic-pituitary-adrenal axis (HPA) in relation to alexithymia in patients with somatoform disorders (SFD). Diurnal salivary cortisol was sampled in 32 patients with SFD who also underwent a psychiatric examination and filled in questionnaires (Toronto Alexithymia Scale, TAS scale; Screening for Somatoform Symptoms, SOMS scale; Hamilton Depression Scale, HAMD). The mean TAS total score in the sample was 55.69.6, 32% of patients being classified as alexithymic on the basis of their TAS scores. Depression scores were moderate (HAMD=13.2, Beck Depression Inventory, BDI=16.5). The patients' alexithymia scores (TAS scale Difficulty identifying feelings) correlated significantly positively with their somatization scale scores (Symptom Checklist-90 Revised, SCL-90-R); r=0.3438 (P0.05) and their scores on the Global Severity Index (GSI) on the SCL-90-R; r=0.781 (P0.01). Regression analysis was performed with cortisol variables as the dependent variables. Cortisol levels [measured by the area under the curve-ground (AUC-G), area under the curve-increase (AUC-I) and morning cortisol (MCS)] were best predicted in a multiple linear regression model by lower depressive scores (HAMD) and more psychopathological symptoms (SCL-90-R). No significant correlations were found between the patients' alexithymia scores (TAS) and cortisol levels. The healthy control group (n=25) demonstrated significantly higher cortisol levels than did the patients with SFD; in both tests P0.001 for AUC-G and AUC-I. However, the two groups did not differ in terms of their mean morning cortisol levels (P0.05). The results suggest that pre-existing hypocortisolism might possibly be associated with SFD.
Original languageEnglish
Pages (from-to)366-373
Number of pages8
JournalNordic Journal of Psychiatry
Volume62
Issue number5
DOIs
Publication statusPublished - 2008

Keywords

  • alexithymia
  • cortisol
  • Somatoform disorders

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    Pedrosa Gil, F., Bidlingmaier, M., Ridout, N., Scheidt, C. E., Caton, S., Schoechlin, C., & Nickel, M. (2008). The relationship between alexithymia and salivary cortisol levels in somatoform disorders. Nordic Journal of Psychiatry , 62(5), 366-373. https://doi.org/10.1080/08039480801983554