TY - JOUR
T1 - The use of the Reichert ocular response analyser to establish the relationship between ocular hysteresis, corneal resistance factor and central corneal thickness in normal eyes
AU - Shah, Sunil
AU - Laiquzzaman, Mohammed
AU - Cunliffe, Ian
AU - Mantry, Sanjay
PY - 2006/12/1
Y1 - 2006/12/1
N2 - Purpose: The aim of this study was to measure ocular hysteresis and corneal resistance factor (CRF), novel methods of analysing ocular rigidity/elasticity and to determine the relationship between central corneal thickness (CCT), hysteresis and CRF in normal subjects. Design: Prospective, cross-sectional, clinical trial. Participants: The study included 207 normal eyes. Methods: Hysteresis and CRF were measured by the ocular response analyser. The CCT was measured using a hand held ultrasonic pachymeter. Main outcome measures: Ocular hysteresis and CRF in normal patients and their relationship with CCT. Results: The mean hysteresis was 10.7 ± 2.0 mmHg standard deviation (S.D.) (range 6.1-17.6 mmHg); the mean CRF was 10.3 ± 2.0 (range 5.7-17.1 mmHg). The mean CCT was 545.0 ± 36.4 μm (471-650 μm). The relationship between hysteresis and CCT; CRF and CCT; CRF and hysteresis were significant (p < 0.0001). Conclusion: This study demonstrated that corneal hysteresis increased with increasing CCT, however, the correlation was moderate. It would appear that CCT, hysteresis and CRF may measure different biomechanical aspects of ocular rigidity and are likely to be useful additional measurement to CCT in the assessment of ocular rigidity when measuring intraocular pressure (IOP). This may be of particular importance when trying to correct IOP measurements for increased or decreased ocular rigidity.
AB - Purpose: The aim of this study was to measure ocular hysteresis and corneal resistance factor (CRF), novel methods of analysing ocular rigidity/elasticity and to determine the relationship between central corneal thickness (CCT), hysteresis and CRF in normal subjects. Design: Prospective, cross-sectional, clinical trial. Participants: The study included 207 normal eyes. Methods: Hysteresis and CRF were measured by the ocular response analyser. The CCT was measured using a hand held ultrasonic pachymeter. Main outcome measures: Ocular hysteresis and CRF in normal patients and their relationship with CCT. Results: The mean hysteresis was 10.7 ± 2.0 mmHg standard deviation (S.D.) (range 6.1-17.6 mmHg); the mean CRF was 10.3 ± 2.0 (range 5.7-17.1 mmHg). The mean CCT was 545.0 ± 36.4 μm (471-650 μm). The relationship between hysteresis and CCT; CRF and CCT; CRF and hysteresis were significant (p < 0.0001). Conclusion: This study demonstrated that corneal hysteresis increased with increasing CCT, however, the correlation was moderate. It would appear that CCT, hysteresis and CRF may measure different biomechanical aspects of ocular rigidity and are likely to be useful additional measurement to CCT in the assessment of ocular rigidity when measuring intraocular pressure (IOP). This may be of particular importance when trying to correct IOP measurements for increased or decreased ocular rigidity.
KW - Central corneal thickness
KW - Elasticity
KW - Hysteresis
KW - Rigidity
UR - http://www.scopus.com/inward/record.url?scp=33750995542&partnerID=8YFLogxK
UR - https://www.sciencedirect.com/science/article/pii/S1367048406001317?via%3Dihub
U2 - 10.1016/j.clae.2006.09.006
DO - 10.1016/j.clae.2006.09.006
M3 - Article
C2 - 17085066
AN - SCOPUS:33750995542
SN - 1367-0484
VL - 29
SP - 257
EP - 262
JO - Contact Lens and Anterior Eye
JF - Contact Lens and Anterior Eye
IS - 5
ER -