The value of magnetoencephalography to guide electrode implantation in epilepsy

S. Seri, Z. Agirre-Arrizubieta, J.N. Thai, P.L. Furlong, R.P. Selway, R.D. Elwes, G. Alarcón

Research output: Contribution to journalMeeting abstract

Abstract

Purpose: To investigate if magnetoencephalography (MEG) can identify implantation sites for intracranial recordings (IR).
Method: Two groups of 12 patients assessed for surgery with IR with and without MEG were compared (MEG and control groups). In the control group, non-invasive presurgical assessment without MEG suggested clear hypotheses for implantation. In the MEG group, non-invasive assessment was inconclusive, and MEG was used to identify implantation sites. Both groups were matched for implantation type. The success of implantation was defined by findings in IR: a) Focal seizure onset; b)Unilateral focal abnormal responses to single pulse electrical stimulation(SPES); and c) Concordance between a) and b).
Results: In all MEG patients, at least one virtual MEG electrode generated suitable hypotheses for the location of implantations. The proportion of patients showing focal seizure onset restricted to one hemisphere was similar in control and MEG groups (6/12 vs. 11/12, Fisher’s exact test,p = 0.0686). The proportion of patients showing unilateral responses to SPES was lower in the control than in the MEG group (7/12 vs. 12/12,p = 0.0373).
Conclusion: The MEG group showed similar or higher incidence of successful implantations than controls.
Original languageEnglish
Article numberP902
Pages (from-to)283-284
Number of pages2
JournalEpilepsia
Volume54
Issue numberS3
DOIs
Publication statusPublished - Jun 2013
Event30th international epilepsy congress - Montreal, Canada
Duration: 23 Jun 201327 Jun 2013

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Magnetoencephalography
Epilepsy
Electrodes
Control Groups
Electric Stimulation
Seizures
Research Design

Bibliographical note

Special Issue: 30th International Epilepsy Congress, Montreal, Canada, 23 – 27 June 2013

Cite this

Seri, S., Agirre-Arrizubieta, Z., Thai, J. N., Furlong, P. L., Selway, R. P., Elwes, R. D., & Alarcón, G. (2013). The value of magnetoencephalography to guide electrode implantation in epilepsy. Epilepsia, 54(S3), 283-284. [P902]. https://doi.org/10.1111/epi.12229
Seri, S. ; Agirre-Arrizubieta, Z. ; Thai, J.N. ; Furlong, P.L. ; Selway, R.P. ; Elwes, R.D. ; Alarcón, G. / The value of magnetoencephalography to guide electrode implantation in epilepsy. In: Epilepsia. 2013 ; Vol. 54, No. S3. pp. 283-284.
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Seri, S, Agirre-Arrizubieta, Z, Thai, JN, Furlong, PL, Selway, RP, Elwes, RD & Alarcón, G 2013, 'The value of magnetoencephalography to guide electrode implantation in epilepsy', Epilepsia, vol. 54, no. S3, P902, pp. 283-284. https://doi.org/10.1111/epi.12229

The value of magnetoencephalography to guide electrode implantation in epilepsy. / Seri, S.; Agirre-Arrizubieta, Z.; Thai, J.N.; Furlong, P.L.; Selway, R.P.; Elwes, R.D.; Alarcón, G.

In: Epilepsia, Vol. 54, No. S3, P902, 06.2013, p. 283-284.

Research output: Contribution to journalMeeting abstract

TY - JOUR

T1 - The value of magnetoencephalography to guide electrode implantation in epilepsy

AU - Seri, S.

AU - Agirre-Arrizubieta, Z.

AU - Thai, J.N.

AU - Furlong, P.L.

AU - Selway, R.P.

AU - Elwes, R.D.

AU - Alarcón, G.

N1 - Special Issue: 30th International Epilepsy Congress, Montreal, Canada, 23 – 27 June 2013

PY - 2013/6

Y1 - 2013/6

N2 - Purpose: To investigate if magnetoencephalography (MEG) can identify implantation sites for intracranial recordings (IR).Method: Two groups of 12 patients assessed for surgery with IR with and without MEG were compared (MEG and control groups). In the control group, non-invasive presurgical assessment without MEG suggested clear hypotheses for implantation. In the MEG group, non-invasive assessment was inconclusive, and MEG was used to identify implantation sites. Both groups were matched for implantation type. The success of implantation was defined by findings in IR: a) Focal seizure onset; b)Unilateral focal abnormal responses to single pulse electrical stimulation(SPES); and c) Concordance between a) and b).Results: In all MEG patients, at least one virtual MEG electrode generated suitable hypotheses for the location of implantations. The proportion of patients showing focal seizure onset restricted to one hemisphere was similar in control and MEG groups (6/12 vs. 11/12, Fisher’s exact test,p = 0.0686). The proportion of patients showing unilateral responses to SPES was lower in the control than in the MEG group (7/12 vs. 12/12,p = 0.0373).Conclusion: The MEG group showed similar or higher incidence of successful implantations than controls.

AB - Purpose: To investigate if magnetoencephalography (MEG) can identify implantation sites for intracranial recordings (IR).Method: Two groups of 12 patients assessed for surgery with IR with and without MEG were compared (MEG and control groups). In the control group, non-invasive presurgical assessment without MEG suggested clear hypotheses for implantation. In the MEG group, non-invasive assessment was inconclusive, and MEG was used to identify implantation sites. Both groups were matched for implantation type. The success of implantation was defined by findings in IR: a) Focal seizure onset; b)Unilateral focal abnormal responses to single pulse electrical stimulation(SPES); and c) Concordance between a) and b).Results: In all MEG patients, at least one virtual MEG electrode generated suitable hypotheses for the location of implantations. The proportion of patients showing focal seizure onset restricted to one hemisphere was similar in control and MEG groups (6/12 vs. 11/12, Fisher’s exact test,p = 0.0686). The proportion of patients showing unilateral responses to SPES was lower in the control than in the MEG group (7/12 vs. 12/12,p = 0.0373).Conclusion: The MEG group showed similar or higher incidence of successful implantations than controls.

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U2 - 10.1111/epi.12229

DO - 10.1111/epi.12229

M3 - Meeting abstract

VL - 54

SP - 283

EP - 284

JO - Epilepsia

JF - Epilepsia

SN - 0013-9580

IS - S3

M1 - P902

ER -

Seri S, Agirre-Arrizubieta Z, Thai JN, Furlong PL, Selway RP, Elwes RD et al. The value of magnetoencephalography to guide electrode implantation in epilepsy. Epilepsia. 2013 Jun;54(S3):283-284. P902. https://doi.org/10.1111/epi.12229