Three-dimensional calibration targets for optical coherence tomography

Michelle G. Sandrian; Peter H. Tomlins; Peter D. Woolliams; Janarthanan Rasakanthan; Graham C.B. Lee; Anna Yang; Boris Považay; Aneesh Alex; Kate Sugden; Wolfgang Drexler

doi:10.1117/12.907748

Three-dimensional calibration targets for optical coherence tomography

Michelle G. Sandrian, Peter H. Tomlins, Peter D. Woolliams, Janarthanan Rasakanthan, Graham C.B. Lee, Anna Yang, Boris Považay, Aneesh Alex, Kate Sugden, Wolfgang Drexler

Aston Institute of Photonic Technologies (AiPT)

Research output: Chapter in Book/Published conference output › Conference publication

Abstract

The recent expansion of clinical applications for optical coherence tomography (OCT) is driving the development of approaches for consistent image acquisition. There is a simultaneous need for time-stable, easy-to-use imaging targets for calibration and standardization of OCT devices. We present calibration targets consisting of three-dimensional structures etched into nanoparticle-embedded resin. Spherical iron oxide nanoparticles with a predominant particle diameter of 400 nm were homogeneously dispersed in a two part polyurethane resin and allowed to harden overnight. These samples were then etched using a precision micromachining femtosecond laser with a center wavelength of 1026 nm, 100kHz repetition rate and 450 fs pulse duration. A series of lines in depth were etched, varying the percentage of inscription energy and speed of the translation stage moving the target with respect to the laser. Samples were imaged with a dual wavelength spectral-domain OCT system and point-spread function of nanoparticles within the target was measured.

Original language	English
Title of host publication	Optical diagnostics and sensing XII
Subtitle of host publication	toward point-of-care diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV
Editors	Robert J. Nordstrom, Gerard L. Coté
Publisher	SPIE
Number of pages	7
Volume	8229
DOIs	https://doi.org/10.1117/12.907748
Publication status	Published - Jan 2012
Event	Optical diagnostics and sensing XII: Toward Point-of-Care Diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV - San Francisco, CA, United States Duration: 21 Jan 2012 → …

Publication series

Name	SPIE proceedings
Publisher	SPIE
Volume	8229
ISSN (Print)	0277-786X

Conference

Conference	Optical diagnostics and sensing XII: Toward Point-of-Care Diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV
Country/Territory	United States
City	San Francisco, CA
Period	21/01/12 → …

Bibliographical note

Sandrian, Michelle G.; Tomlins, Peter H.; Woolliams, Peter D.; Rasakanthan, Janarthanan; Lee, Graham C.B.; Yang, Anna; Považay, Boris; Alex, Aneesh; Sugden, Kate; Drexler, Wolfgang, "Three-dimensional calibration targets for optical coherence tomography". Optical diagnostics and sensing XII: toward point-of-care diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV., ed. Robert J. Nordstrom; Gerard L. Coté. Vol. 8229 SPIE, 2012. (SPIE proceedings).

Copyright 2012 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic electronic or print reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

http://dx.doi.org/10.1117/12.907748

Keywords

calibration target
optical coherence tomography
femtosecond inscription
point-spread function

Access to Document

10.1117/12.907748

Three-dimensional calibration targets for optical coherence tomography
Sandrian, Michelle G.; Tomlins, Peter H.; Woolliams, Peter D.; Rasakanthan, Janarthanan; Lee, Graham C.B.; Yang, Anna; Považay, Boris; Alex, Aneesh; Sugden, Kate; Drexler, Wolfgang, "Three-dimensional calibration targets for optical coherence tomography". Optical diagnostics and sensing XII: toward point-of-care diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV., ed. Robert J. Nordstrom; Gerard L. Coté. Vol. 8229 SPIE, 2012. (SPIE proceedings). Copyright 2012 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic electronic or print reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. http://dx.doi.org/10.1117/12.907748
Final published version, 1.2 MB

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Sandrian, M. G., Tomlins, P. H., Woolliams, P. D., Rasakanthan, J., Lee, G. C. B., Yang, A., Považay, B., Alex, A., Sugden, K., & Drexler, W. (2012). Three-dimensional calibration targets for optical coherence tomography. In R. J. Nordstrom, & G. L. Coté (Eds.), Optical diagnostics and sensing XII: toward point-of-care diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV (Vol. 8229). (SPIE proceedings; Vol. 8229). SPIE. https://doi.org/10.1117/12.907748

Sandrian, Michelle G. ; Tomlins, Peter H. ; Woolliams, Peter D. et al. / Three-dimensional calibration targets for optical coherence tomography. Optical diagnostics and sensing XII: toward point-of-care diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV. editor / Robert J. Nordstrom ; Gerard L. Coté. Vol. 8229 SPIE, 2012. (SPIE proceedings).

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abstract = "The recent expansion of clinical applications for optical coherence tomography (OCT) is driving the development of approaches for consistent image acquisition. There is a simultaneous need for time-stable, easy-to-use imaging targets for calibration and standardization of OCT devices. We present calibration targets consisting of three-dimensional structures etched into nanoparticle-embedded resin. Spherical iron oxide nanoparticles with a predominant particle diameter of 400 nm were homogeneously dispersed in a two part polyurethane resin and allowed to harden overnight. These samples were then etched using a precision micromachining femtosecond laser with a center wavelength of 1026 nm, 100kHz repetition rate and 450 fs pulse duration. A series of lines in depth were etched, varying the percentage of inscription energy and speed of the translation stage moving the target with respect to the laser. Samples were imaged with a dual wavelength spectral-domain OCT system and point-spread function of nanoparticles within the target was measured.",

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language = "English",

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Sandrian, MG, Tomlins, PH, Woolliams, PD, Rasakanthan, J, Lee, GCB, Yang, A, Považay, B, Alex, A, Sugden, K & Drexler, W 2012, Three-dimensional calibration targets for optical coherence tomography. in RJ Nordstrom & GL Coté (eds), Optical diagnostics and sensing XII: toward point-of-care diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV. vol. 8229, SPIE proceedings, vol. 8229, SPIE, Optical diagnostics and sensing XII: Toward Point-of-Care Diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV, San Francisco, CA, United States, 21/01/12. https://doi.org/10.1117/12.907748

Three-dimensional calibration targets for optical coherence tomography. / Sandrian, Michelle G.; Tomlins, Peter H.; Woolliams, Peter D. et al.
Optical diagnostics and sensing XII: toward point-of-care diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV. ed. / Robert J. Nordstrom; Gerard L. Coté. Vol. 8229 SPIE, 2012. (SPIE proceedings; Vol. 8229).

Research output: Chapter in Book/Published conference output › Conference publication

TY - GEN

T1 - Three-dimensional calibration targets for optical coherence tomography

AU - Sandrian, Michelle G.

AU - Tomlins, Peter H.

AU - Woolliams, Peter D.

AU - Rasakanthan, Janarthanan

AU - Lee, Graham C.B.

AU - Yang, Anna

AU - Považay, Boris

AU - Alex, Aneesh

AU - Sugden, Kate

AU - Drexler, Wolfgang

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N2 - The recent expansion of clinical applications for optical coherence tomography (OCT) is driving the development of approaches for consistent image acquisition. There is a simultaneous need for time-stable, easy-to-use imaging targets for calibration and standardization of OCT devices. We present calibration targets consisting of three-dimensional structures etched into nanoparticle-embedded resin. Spherical iron oxide nanoparticles with a predominant particle diameter of 400 nm were homogeneously dispersed in a two part polyurethane resin and allowed to harden overnight. These samples were then etched using a precision micromachining femtosecond laser with a center wavelength of 1026 nm, 100kHz repetition rate and 450 fs pulse duration. A series of lines in depth were etched, varying the percentage of inscription energy and speed of the translation stage moving the target with respect to the laser. Samples were imaged with a dual wavelength spectral-domain OCT system and point-spread function of nanoparticles within the target was measured.

AB - The recent expansion of clinical applications for optical coherence tomography (OCT) is driving the development of approaches for consistent image acquisition. There is a simultaneous need for time-stable, easy-to-use imaging targets for calibration and standardization of OCT devices. We present calibration targets consisting of three-dimensional structures etched into nanoparticle-embedded resin. Spherical iron oxide nanoparticles with a predominant particle diameter of 400 nm were homogeneously dispersed in a two part polyurethane resin and allowed to harden overnight. These samples were then etched using a precision micromachining femtosecond laser with a center wavelength of 1026 nm, 100kHz repetition rate and 450 fs pulse duration. A series of lines in depth were etched, varying the percentage of inscription energy and speed of the translation stage moving the target with respect to the laser. Samples were imaged with a dual wavelength spectral-domain OCT system and point-spread function of nanoparticles within the target was measured.

KW - calibration target

KW - optical coherence tomography

KW - femtosecond inscription

KW - point-spread function

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DO - 10.1117/12.907748

M3 - Conference publication

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T3 - SPIE proceedings

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A2 - Coté, Gerard L.

PB - SPIE

T2 - Optical diagnostics and sensing XII: Toward Point-of-Care Diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV

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ER -

Sandrian MG, Tomlins PH, Woolliams PD, Rasakanthan J, Lee GCB, Yang A et al. Three-dimensional calibration targets for optical coherence tomography. In Nordstrom RJ, Coté GL, editors, Optical diagnostics and sensing XII: toward point-of-care diagnostics; and design and performance validation of phantoms used in conjunction with optical measurement of tissue IV. Vol. 8229. SPIE. 2012. (SPIE proceedings). doi: 10.1117/12.907748

Three-dimensional calibration targets for optical coherence tomography

Abstract

Publication series

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Bibliographical note

Keywords

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