Tourette syndrome and obsessive compulsive disorder: compulsivity along the continuum

Clare M. Eddy, Andrea E. Cavanna*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

The strong genetic link between obsessive compulsive disorder (OCD) and Tourette syndrome (TS) raises the possibility that obsessions and compulsions may comprise an alternative phenotypic expression of tics. Both of these disorders are characterised by repetitive behaviours (RB) involving recurrent thoughts and/or actions, often linked to dangerous or taboo themes, which present fairly early in life and tend to follow a chronic waxing and waning course. Over time many studies have attempted to disentangle the clinical profiles of these disorders. This article explores the key differences revealed by research over the last few decades, examining the types of RB expressed, patients' accompanying phenomenological experience (e.g. cognitive and sensory correlates), the proposed neural bases for each condition, and common interventions. Attempts to distinguish between OCD and TS based on the specific types of RB have often met with limitations. However, existing literature pertaining to the phenomenological experience of OCD and TS indicates that a number of factors may help differentiate these commonly associated conditions. Furthermore, differences in the psychological and physiological correlates of RB in TS and OCD are broadly in accordance with neuroimaging data. Study findings could offer insight into the predominance of TS diagnosis in males, age-related changes in diagnoses and the association between more context-dependent tic-like behaviours and OCD in patients with TS. Future studies should explore relationships between the cognitive, emotional and sensory aspects of RB and patients' demographical characteristics, neuropsychological test performance, and neural profiles.

Original languageEnglish
Pages (from-to)363-371
Number of pages9
JournalJournal of Obsessive-Compulsive and Related Disorders
Volume3
Issue number4
Early online date13 Apr 2014
DOIs
Publication statusPublished - Oct 2014

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Tourette Syndrome
Obsessive-Compulsive Disorder
Tics
Taboo
Obsessive Behavior
Neuropsychological Tests
Neuroimaging
Psychology
Research

Keywords

  • obsessive compulsive disorder
  • repetitive behaviours
  • tics
  • Tourette syndrome

Cite this

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abstract = "The strong genetic link between obsessive compulsive disorder (OCD) and Tourette syndrome (TS) raises the possibility that obsessions and compulsions may comprise an alternative phenotypic expression of tics. Both of these disorders are characterised by repetitive behaviours (RB) involving recurrent thoughts and/or actions, often linked to dangerous or taboo themes, which present fairly early in life and tend to follow a chronic waxing and waning course. Over time many studies have attempted to disentangle the clinical profiles of these disorders. This article explores the key differences revealed by research over the last few decades, examining the types of RB expressed, patients' accompanying phenomenological experience (e.g. cognitive and sensory correlates), the proposed neural bases for each condition, and common interventions. Attempts to distinguish between OCD and TS based on the specific types of RB have often met with limitations. However, existing literature pertaining to the phenomenological experience of OCD and TS indicates that a number of factors may help differentiate these commonly associated conditions. Furthermore, differences in the psychological and physiological correlates of RB in TS and OCD are broadly in accordance with neuroimaging data. Study findings could offer insight into the predominance of TS diagnosis in males, age-related changes in diagnoses and the association between more context-dependent tic-like behaviours and OCD in patients with TS. Future studies should explore relationships between the cognitive, emotional and sensory aspects of RB and patients' demographical characteristics, neuropsychological test performance, and neural profiles.",
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Tourette syndrome and obsessive compulsive disorder : compulsivity along the continuum. / Eddy, Clare M.; Cavanna, Andrea E.

In: Journal of Obsessive-Compulsive and Related Disorders, Vol. 3, No. 4, 10.2014, p. 363-371.

Research output: Contribution to journalArticle

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