Triggering up states in all-to-all coupled neurons

H. V.V. Ngo, J. Köhler, J. Mayer, J. C. Claussen, H. G. Schuster

Research output: Contribution to journalArticlepeer-review


Slow-wave sleep in mammalians is characterized by a change of large-scale cortical activity currently paraphrased as cortical Up/Down states. A recent experiment demonstrated a bistable collective behaviour in ferret slices, with the remarkable property that the Up states can be switched on and off with pulses, or excitations, of same polarity; whereby the effect of the second pulse significantly depends on the time interval between the pulses. Here we present a simple time-discrete model of a neural network that exhibits this type of behaviour, as well as quantitatively reproduces the time dependence found in the experiments.

Original languageEnglish
Article number68002
Issue number6
Publication statusPublished - 13 Apr 2010


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