Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2 and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand

Eleyna M Martin, Joanne C. Clark, Samantha J Montague, Luis A. Moran, Ying Di, Lily J. Bull, Luke Whittle, Florije Raka, Richard J. Buka, Idrees Zafar, Caroline Kardeby, Alexandre Slater, Steve P. Watson*

*Corresponding author for this work

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Medicine & Life Sciences