Two dimensional population balance modelling of crystal growth behaviour under the influence of impurities

Yang Zhang, Jing Jing Liu, Jian Wan, Xue Z. Wang

Research output: Contribution to journalArticlepeer-review

Abstract

This short communication investigates the impact of impurity on crystal growth behaviour in terms of crystal shape distribution. A two dimensional population balance model is applied to study the crystal shape changing behaviour in cooling crystallisation producing β-form L-glutamic acid crystals, in the presence and without the presence of an additive, L-phenylalanine. The simulation results were verified in experiments using a 1-litre crystalliser for crystallisation of L-glutamic acid.
Original languageEnglish
Pages (from-to)672-678
JournalAdvanced Powder Technology
Volume26
Issue number2
Early online date16 Jan 2015
DOIs
Publication statusPublished - Mar 2015

Keywords

  • Impurity
  • Additives
  • Crystal shape distribution control
  • Morphological population balance
  • L-Glutamic acid

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