Abstract
The work considers a theranostic system that implements a multimodal approach allowing the simultaneous generation of singlet oxygen and visualization of the various parameters of the vascular bed. The system, together with the developed data processing algorithm, has the ability to assess architectural changes in the vascular network and its blood supply, as well as to identify periodic signal changes associated with mechanisms of blood flow oscillation of various natures. The use of this system seems promising in studying the effect of laser-induced singlet oxygen on the state of the vascular bed, as well as within the framework of the theranostic concept of treatment and diagnosis of oncological diseases and non-oncological vascular anomalies.
| Original language | English |
|---|---|
| Pages (from-to) | 1137-1140 |
| Number of pages | 4 |
| Journal | Optics Letters |
| Volume | 49 |
| Issue number | 5 |
| Early online date | 20 Feb 2024 |
| DOIs | |
| Publication status | Published - 1 Mar 2024 |
Bibliographical note
Publisher Copyright:© 2024 Optica Publishing Group.
Funding
Funding. Russian Science Foundation (21-75-00086). Acknowledgment. The authors acknowledge the support of the Russian Science Foundation under project No. 21-75-00086. Disclosures. The authors declare no conflicts of interest. Data availability. Data underlying the results presented in this paper are not publicly available at this time but may be obtained from the authors upon reasonable request.
| Funders | Funder number |
|---|---|
| Russian Science Foundation | 21-75-00086 |
Keywords
- Singlet Oxygen
- Precision Medicine
- Photoplethysmography
- Diagnostic Imaging
- Lasers
- Optical Imaging
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