The article is aimed at conducting pilot studies of microcirculation changes in patients with diabetes mellitus during the course of intravenous infusions of alpha lipoic acid. The study was conducted with patients with diabetes during the passage of a standard course of treatment. The change in parameters was compared before the start of the infusion course, during and after the course. A system of wearable laser Doppler monitors was used to conduct the study. The study showed that although the microcirculation index does not undergo significant changes during the treatment process, spectral analysis of the recorded signal has potential applicability. Further studies with a larger sample group are required for a qualitative analysis of the observed effects.
|Proceedings of SPIE - The International Society for Optical Engineering
|Published - 2 Apr 2020
|Tissue Optics and Photonics 2020 - None, France
Duration: 6 Apr 2020 → 10 Apr 2020
Bibliographical noteCopyright 2020 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
This study was funded by the Russian Science Foundation (the research project 18-79-00237).
- Alpha lipoic acid
- Diabetic neuropathy
- Laser Doppler flowmetry
- Skin blood flow
- Wearable electronics