Wound healing studies and interfacial phenomena: use and relevance of the corneal model

Aisling M. Mann, Brian J Tighe

Research output: Chapter in Book/Published conference outputChapter


The interaction of the wound dressing as a biomaterial with the wound bed is the central issue of this chapter. The interfacial phenomenon that encompasses the biological and biochemical consequences that arise when a biomaterial is introduced to a host biological environment is discussed. A great deal can be learned from observations arising from the behaviour of biomaterials at other body sites; one particularly relevant body site in the context of wound healing is the anterior eye. The cornea, tear film and posterior surface of the contact lens provide an informative model of the parallel interface that exists between the chronic wound bed, wound fluid and the dressing biomaterial. © 2011 Woodhead Publishing Limited All rights reserved.
Original languageEnglish
Title of host publicationAdvanced wound repair therapies
EditorsDavid Farrar
Place of PublicationCambridge (UK)
Number of pages37
ISBN (Print)978-1-84569-700-6
Publication statusPublished - 21 Jun 2011


  • wound dressing biomaterials
  • compatibility
  • wound response
  • corneal model
  • wound healing
  • biomaterial studies
  • interfacial phenomena
  • ocular surface contact lens
  • wound fluid
  • tear film collection
  • biomaterials
  • mucosal wound healing


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