Xenotransplantation as a Business Solution to the Organ Shortage

Christopher Bobier; Richard Byron Gibson; Anthony Merlocco; Daniel Rodger; Daniel J. Hurst

doi:10.1111/bioe.13397

Xenotransplantation as a Business Solution to the Organ Shortage

Christopher Bobier^*, Richard Byron Gibson, Anthony Merlocco, Daniel Rodger, Daniel J. Hurst

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Xenotransplantation has the potential to alter the U.S. transplant system in profound ways. However, this emerging “spare parts” solution spearheaded by biotechnology companies raises concerns about its impact on the organ shortage, healthcare systems, population health, and health inequalities. We contend that xenotransplantation may have limited benefits in improving health, could prove prohibitively expensive for many, and may divert resources away from proven public health measures. Additionally, it carries the risk of perpetuating stigma. Xenotransplantation may thereby exacerbate existing healthcare inequities across racial, ethnic, socio-economic, and geographic lines. To mitigate these risks, we contend that public health expert input is integral for xenotransplant policy development and outreach and that this underscores the importance of federal government investment in transplant infrastructure.

Original language	English
Number of pages	9
Journal	Bioethics
DOIs	https://doi.org/10.1111/bioe.13397
Publication status	E-pub ahead of print - 29 Jan 2025

Bibliographical note

Copyright © 2025 John Wiley & Sons Ltd. This is the peer reviewed version of the following article: Bobier, C, Gibson, RB, Merlocco, A, Rodger, D & Hurst, DJ 2025, 'Xenotransplantation as a Business Solution to the Organ Shortage', Bioethics.
which has been published in final form at https://doi.org/10.1111/bioe.13397. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited

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title = "Xenotransplantation as a Business Solution to the Organ Shortage",

abstract = "Xenotransplantation has the potential to alter the U.S. transplant system in profound ways. However, this emerging “spare parts” solution spearheaded by biotechnology companies raises concerns about its impact on the organ shortage, healthcare systems, population health, and health inequalities. We contend that xenotransplantation may have limited benefits in improving health, could prove prohibitively expensive for many, and may divert resources away from proven public health measures. Additionally, it carries the risk of perpetuating stigma. Xenotransplantation may thereby exacerbate existing healthcare inequities across racial, ethnic, socio-economic, and geographic lines. To mitigate these risks, we contend that public health expert input is integral for xenotransplant policy development and outreach and that this underscores the importance of federal government investment in transplant infrastructure.",

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note = "Copyright {\textcopyright} 2025 John Wiley & Sons Ltd. This is the peer reviewed version of the following article: Bobier, C, Gibson, RB, Merlocco, A, Rodger, D & Hurst, DJ 2025, 'Xenotransplantation as a Business Solution to the Organ Shortage', Bioethics. which has been published in final form at https://doi.org/10.1111/bioe.13397. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley{\textquoteright}s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited ",

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N1 - Copyright © 2025 John Wiley & Sons Ltd. This is the peer reviewed version of the following article: Bobier, C, Gibson, RB, Merlocco, A, Rodger, D & Hurst, DJ 2025, 'Xenotransplantation as a Business Solution to the Organ Shortage', Bioethics. which has been published in final form at https://doi.org/10.1111/bioe.13397. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited

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Xenotransplantation as a Business Solution to the Organ Shortage

Abstract

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