Abstract
Quiescent thymocytes are stimulated to divide by a variety of compounds. These may be subdivided into four categories.The first group includes parathyroid hormone, vitamin D3 and
its metabolites and raised extracellular calcium concentrations. Enhanced calcium influx provoked directly or possibly via cGMP production is the prelude to calmodulin activation which subsequently triggers cell arousal by a process which is independent of magnesium ions. High oestradiol concentrations by further increasing intra— cellular calcium concentrations beyond a threshold inhibit this response...
| Date of Award | 1983 |
|---|---|
| Original language | English |
| Awarding Institution |
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Keywords
- Stimulus-mitosis coupling
- rat
- thymic lymphocyte