Abstract
The structures of four compounds are reported, having been determined by single crystal X-ray crystallography. The four compounds fall into two categories :-Protonated antifolates with anions
Substituted antifolates.
The first category has been complemented with molecular orbital calculations on protonated and unprotonated :-
2-amino-4-oxo-pyrimidines (2-aminopyrimidin-4-ones)
2,4 diaminopyrimidines
triazines.
Further calculations are reported on one of the structures to determine whether the atoms appear to be in a minimum energy position.
| Date of Award | 1987 |
|---|---|
| Original language | English |
| Awarding Institution |
|