Excipients in medicines for children: scientific and regulatory paradigms

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Abstract

There is an ongoing debate over the use of pharmaceutical excipients in medicines for children, triggered by the increased number of formulations suitable for this target patient population. Pharmaceutical excipients can be regarded as essential / necessary enablers in formulation development. These are materials other than the 'active pharmaceutical ingredient' which are added to the formulation to achieve a specific function1. This may include aiding in the processing or manufacture of the drug delivery system such as lubricants or flow aids, controlling the release of the active ingredient to achieve modified release, enhance patient acceptability by improving taste of medicines or to develop easily swallowed dosage forms.

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Details

Original languageEnglish
Pages (from-to)67-70
Number of pages4
JournalEuropean Pharmaceutical Review
Volume19
Issue number2
Publication statusPublished - 15 Apr 2014

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