Long-period fibre grating based biosensor for detection of DNA hybridisation

Xianfeng F. Chen, Marcus D. Hughes, Kaiming Zhou, Edward Davies, Lin Zhang, Anna V. Hine, Ian Bennion

Research output: Chapter in Book/Published conference outputChapter

Abstract

We implement an optical biosensor using long-period fibre grating immobilised with probe DNA. It has been used to detect hybridisation of target DNA, showing a high sensitivity and reusability function.
Original languageEnglish
Title of host publicationBragg Gratings, Photosensitivity, and Poling in Glass Waveguides, OSA Technical Digest (CD)
Publication statusPublished - Sept 2007

Bibliographical note

Bragg Gratings, Photosensitivity, and Poling in Glass Waveguides (BGPP), Quebec City (CA), 2 September 2007. This paper was published in OSA Technical Digest and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI=BGPP-2007-BTuE4. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law. © 2007 Optical Society of America.

Keywords

  • optical biosensor
  • long-period fibre grating
  • probe DNA
  • hybridisation
  • target DNA
  • sensitivity
  • reusability

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