Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies

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Abstract

BACKGROUND: Food allergy can have a significant impact on health related quality of life (HRQoL). Parental proxy questionnaires are commonly used when children are too young to complete questionnaires themselves. Little data is available on HRQoL in children with non-IgE-mediated gastrointestinal food allergy (GIFA). The aim of this study was to evaluate HRQoL in these children by parent proxy.

METHODS: A cross-sectional questionnaire study was conducted with children 2-16 years old with confirmed (GIFA). Parents of these children completed the Paediatric Quality of Life Inventory (PedsQL(™) ) and the Family Impact module of the PedsQL. The PedsQL scores were compared to two published cohorts: functional abdominal pain (FAP) and IgE-mediated food allergy.

RESULTS: Fifty-two parents of children with GIFA completed the PedsQL(™) parent proxy. The GIFA cohort had significantly better overall HRQoL compared to the FAP cohort, but lower emotional functioning scores. The GIFA cohort also had poorer physical QoL compared to the IgE cohort (all p<0.05). The more foods excluded, comorbidity of nasal congestion, abdominal pain, back arching, the persistence of flatus and gastrointestinal symptom severity after elimination diet were related to poorer QoL in this non-IgE cohort. Regression analyses showed that number of foods and nasal congestion significantly predicted total QoL score as perceived by parents.

CONCLUSIONS: This study has shown that different areas of HRQoL of children with GIFA are affected compared to children with FAP or IgE-mediated food allergy, highlighting the need for a specific GIFA HRQoL questionnaire to better understand the impact on these children. This article is protected by copyright. All rights reserved.

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  • Parental perception_child’s Quality of Life_non-Immunoglobulin-E mediated gastrointestinal allergies

    Rights statement: This is the peer reviewed version of the following article: Foong, R. X., Meyer, R., Godwin, H., Dziubak, R., Lozinsky, A. C., Reeve, K., ... Shah, N. (2017). Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies. Paediatric Allergy and Immunology, 28(3), 251-256, which has been published in final form at http://dx.doi.org/10.1111/pai.12689. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

    Accepted author manuscript, 178 KB, PDF-document

Details

Original languageEnglish
Pages (from-to)251-256
Number of pages6
JournalPaediatric Allergy and Immunology
Volume28
Issue number3
Early online date19 Dec 2016
DOIs
Publication statusPublished - May 2017

Bibliographic note

This is the peer reviewed version of the following article: Foong, R. X., Meyer, R., Godwin, H., Dziubak, R., Lozinsky, A. C., Reeve, K., ... Shah, N. (2017). Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies. Paediatric Allergy and Immunology, 28(3), 251-256, which has been published in final form at http://dx.doi.org/10.1111/pai.12689. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

    Keywords

  • gastrointestinal allergies, non-IgE-mediated allergies, paediatrics, quality of life

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