Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Lucy M. Watkins; Adam F. Lee; James W.B. Moir; Karen Wilson

doi:10.1021/acsbiomaterials.6b00705

Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Lucy M. Watkins, Adam F. Lee^*, James W.B. Moir, Karen Wilson

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

Original language	English
Pages (from-to)	88-94
Number of pages	7
Journal	ACS Biomaterials Science and Engineering
Volume	3
Issue number	1
Early online date	12 Dec 2016
DOIs	https://doi.org/10.1021/acsbiomaterials.6b00705
Publication status	Published - 9 Jan 2017

Bibliographical note

This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705

Keywords

biofilm
fibroblast
plasma
polymerization
polyurethane
XPS

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10.1021/acsbiomaterials.6b00705

Plasma generated poly allyl alcohol antifouling coatings for cellular attachmentAccepted author manuscript, 542 KB

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title = "Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment",

abstract = "Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.",

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AU - Watkins, Lucy M.

AU - Lee, Adam F.

AU - Moir, James W.B.

AU - Wilson, Karen

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N2 - Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

AB - Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

KW - biofilm

KW - fibroblast

KW - plasma

KW - polymerization

KW - polyurethane

KW - XPS

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JO - ACS Biomaterials Science and Engineering

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Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Abstract

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Keywords

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