Abstract
Compliant structures are important in several biofluid flow problems including the heart,
lungs and abdominal aortic aneurysms where the walls move under the influence of the fluid pressure
and muscle action. Coronary heart disease (CHD) is a major cause of death in the U.S.A with
approximately 650,000 fatalities a year and involves a progressive constriction of the coronary artery
by atherosclerosis. Blood flow is reduced and when under stress the heart muscle is deprived of oxygen and
nutrients. The blood flow in the coronary artery is strongly influenced by the flexing of the artery wall.
In this work a method for manufacturing silicone models with compliance controlled by the wall thickness
and the cross-wall (transmural) pressure difference, of arteries with varying stenosis (narrowing related to
atherosclerosis and other circulatory diseases), is demonstrated. PIV analysis is used to compare
results between a rigid and compliant straight tube model experiencing a physiological realistic flow wave
with in vivo parameters of time period 1s, mean and peak Reynolds numbers 540 and 920 respectively and a
Womersley number of 4.54. In vitro results are obtained in models scaled to 2.8 times in vivo dimensions.
A method for analysing 3 dimensional surface displacement is used to study the effects of static loading on
compliant models with 30% symmetric and asymmetric stenosis. The results show that at physiologically
relevant levels of compliance there is a variation in the flow field when compared to rigid pipes and that the
surface displacement is dominated by radial motion with a smaller axial motion being present.
lungs and abdominal aortic aneurysms where the walls move under the influence of the fluid pressure
and muscle action. Coronary heart disease (CHD) is a major cause of death in the U.S.A with
approximately 650,000 fatalities a year and involves a progressive constriction of the coronary artery
by atherosclerosis. Blood flow is reduced and when under stress the heart muscle is deprived of oxygen and
nutrients. The blood flow in the coronary artery is strongly influenced by the flexing of the artery wall.
In this work a method for manufacturing silicone models with compliance controlled by the wall thickness
and the cross-wall (transmural) pressure difference, of arteries with varying stenosis (narrowing related to
atherosclerosis and other circulatory diseases), is demonstrated. PIV analysis is used to compare
results between a rigid and compliant straight tube model experiencing a physiological realistic flow wave
with in vivo parameters of time period 1s, mean and peak Reynolds numbers 540 and 920 respectively and a
Womersley number of 4.54. In vitro results are obtained in models scaled to 2.8 times in vivo dimensions.
A method for analysing 3 dimensional surface displacement is used to study the effects of static loading on
compliant models with 30% symmetric and asymmetric stenosis. The results show that at physiologically
relevant levels of compliance there is a variation in the flow field when compared to rigid pipes and that the
surface displacement is dominated by radial motion with a smaller axial motion being present.
Original language | English |
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Pages | 5-8 |
Number of pages | 4 |
Publication status | Published - 2010 |
Event | 15th international symposium of laser techniques to fluid mechanics - Lisbon, Portugal Duration: 5 Jul 2010 → 8 Jul 2010 |
Conference
Conference | 15th international symposium of laser techniques to fluid mechanics |
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Country/Territory | Portugal |
City | Lisbon |
Period | 5/07/10 → 8/07/10 |