The fractal properties of the retinal vascular architecture

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Abstract

Purpose: The human retinal vasculature has been demonstrated to exhibit fractal, or statistically self similar properties. Fractal analysis offers a simple quantitative method to characterise the complexity of the branching vessel network in the retina. Several methods have been proposed to quantify the fractal properties of the retina.
Methods: Twenty five healthy volunteers underwent retinal photography, retinal oximetry and ocular biometry. A robust method to evaluate the fractal properties of the retinal vessels is proposed; it consists of manual vessel segmentation and box counting of 50 degree retinal photographs centred on the fovea.
Results: Data is presented on the associations between the fractal properties of the retinal vessels and various functional properties of the retina.
Conclusion Fractal properties of the retina could offer a promising tool to assess the risk and prognostic factors that define retinal disease. Outstanding efforts surround the need to adopt a standardised protocol for assessing the fractal properties of the retina, and further demonstrate its association with disease processes.

Details

Original languageEnglish
Article numberT014
JournalActa Ophthalmologica
Volume91
Issue numberSuppl.s252
DOIs
Publication statusPublished - 6 Aug 2013
EventEuropean Association for Vision and Eye Research conference 2013 - Nice, France
Duration: 18 Sep 201321 Sep 2013

Bibliographic note

2013 European Association for Vision and Eye Research Conference, 18-21 September 2013, Nice, France.

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