β-Ketosulphinyl chlorides have been prepared by the reaction of isopropyl ketones with thionyl chloride and an attempt has also been made to determine the reaction mechanism from the kinetic data. These compounds show a diastereotopic effect of the gem-dimethyl group or suitably positioned hydrogen atoms. This diastereotapic effect is shown to be due to both intrinsic asymmetry and conformational preferences. β-Ketosulphinyl chlorides undergo cleavage of the carbon-sulphur bond on treatment with certain nucleophiles containing oxygen as the nucleophilic atom...
| Date of Award | Sept 1976 |
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| Original language | English |
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Some aspects of the chemistry of sulphinyl and related compounds
Gupta, R. P. (Author). Sept 1976
Student thesis: Doctoral Thesis › Doctor of Philosophy