• School of Infrastructure and Sustainable Engineering (ISE), College of Engineering and Physical Sciences, Aston University

      B4 7ET Birmingham

      United Kingdom

    Accepting PhD Students

    PhD projects

    Novel methods for the isolation of bone sarcoma biomarkers from liquid biopsies (https://www.findaphd.com/phds/project/novel-methods-for-the-isolation-of-bone-sarcoma-biomarkers-from-liquid-biopsies/?p168676)

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    Personal profile

    Biography

    I obtained my first degree in Chemical Engineering from the National Technical University of Athens (NTUA). I then did a one-year MSc in Biochemical Engineering at University College London (UCL), followed by two years research under the supervision of Prof Peter Dunnill (OBE). I won a Marie Curie Research Training Grant and moved to the Center for Process Biotechnology (CPB) at the Technical University of Denmark (DTU), where I obtained my PhD degree in Biotechnology. In 2002 I took up the position of Senior R&D scientist and Purification team leader at the Pharmaceutical company ALPHARMA (now Xellia Pharmaceuticals), before returning back to the UK as a Senior Research Fellow at the University of Birmingham and then Lecturer in Chemical Engineering at Loughborough University. I joined Aston in November 2015.

    Research Interests

    • Materials and devices for efficient separation and purification of high value biotherapeutics and human cells
    • Edible scaffolds for cultivated meat production

    Qualifications

    • Senior Fellow of the Higher Education Academy (SFHEA)
    • PhD in Biotechnology
    • MSc in Biochemical Engineering
    • MEng in Chemical Engineering

    PhD Supervision

    Current students:

    Alice Johnson - Project title: 'Optimisation of scaffolds for the bioprocessing of lab-grown meat'.

    Louis Hutchings - Project title: '3D printing of edible biomimetic scaffolds for the engineering of animal muscle tissue'.

    Benjamin Dages - Project title: 'Novel microcarriers for scalable clean meat production'.

    Sophie Caprioli - Project title: 'Engineering degradable, ‘tuneable’ microcarriers for the bulk culture of therapeutically active mesenchymal stem cells'.

    Rajan Vraitch - Project title: 'Modelling of the spinal cord for the greater understanding of the aetiology and management of compressive spinal cord pathology'.

    Past students:

    W. Joseph A. Homer - Project title: 'Thermally stabilised, crosslinker-free poly(vinyl alcohol) nanofibers produced by electrospinning: Applications in cell processing and tissue engineering'. Awarded 2024 by Aston University.

    Kinana Aliko - Project title: 'Towards a green route for the synthesis of renewable poly(butylene succinate) antimicrobial fibrous mats'. Awarded 2020 by Aston University.

    Tina Šutar - Project title: ‘New formats for affinity selection of human cells’. Awarded 2015 by Loughborough University.

    William S. C. Bowen - Project title:  ‘Development and characterisation of affinity devices for cell detection and separation’. Awarded 2015 by Loughborough University.

     

    Funding Applications and Awards

    • EPSRC IAA Impact Builder Award. Value: £25,000 (Completed 2023)
    • The Birmingham Orthopaedic Charity. Value: £15,000 (Completed 2023)
    • The Royal Society International Exchanges Award. Value: £11,712 (2019-2023)
    • The Royal Academy of Engineering Visiting Professors Scheme (Academic Champion) (2019-2022)
    • EPSRC AMR4AMR seedcorn fund - 'Novel poly(butylene succinate) fibre dressing with naturally sourced antimicrobial agents for burn wound treatment'. Value: £33,150 (Completed 2018)
    • EPSRC AMR4AMR seedcorn fund - 'Critical points in the pathway of antibiotic prescribing in the hospital setting; the antibiotic mapping of prescribing (ABMAP) study'. Value: £23,149 (Completed 2018)
    • Bioprocessing Research Industry Club/BBSRC Grant (BB/I017143/1) - ‘Developing generic scalable selection methods for human therapeutic cells’. Value: £189,000 (Completed 2015)

    Teaching Activity

    Mass Tansfer (CE2MAT) - Module Leader

    Advanced Process Design Project (CE3APD) - Module contributor

    Research Project (CE4PRJ) - Module Leader

    Downstream Processing for Biotechnology Products (CE4DPB) - Module Leader

    Administrative Roles

    CEAC Student Experience Lead

    Professional/editorial offices

    • Cellular Agriculture Greece - Advisory Board Member
    • Institution of Chemical Engineers Biochemical Engineering Special Interest Group (IChemE BESIG) - Committee Member & Webinar coordinator
    • UK Society for Cell Culture Biotechnology (ESACT-UK) - Committee Member & Deputy Secretary
    • Journal of Chemical Technology and Biotechnology - Editorial Board Member
    • Biotechnology Letters - Editorial Board Member
    • Frontiers in Bioengineering and Biotechnology ‘Bioprocess Engineering’ - Review Editor

    Visiting Appointments

    • Senior Research Fellow honorary appointment at the Royal Orthopaedic Hospital NHS Foundation Trust, UK (since October 2020)

    Contact Details

    Phone number: 0121 204 4702 
    Email: e.theodosiou@aston.ac.uk 
    Room number: MB134

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