A concept of cryoapplicator based on sapphire shaped crystal enabling control of the ice ball formation using spatially resolved elastic backscattering of light

E. N. Dubyanskaya, N. V. Chernomyrdin, I. N. Dolganova, A. A. Kuznetsov, E. E. Mukhina, L. P. Safonova, A. I. Donodin, I. A. Shikunova, K. I. Zaytsev, V. N. Kurlov

Research output: Chapter in Book/Published conference outputConference publication

Abstract

We have proposed a concept of monitoring ice ball formation in biological tissues during cryodestruction process via spatially-resolved detection of elastic light backscattering. For this purpose, we developed an experimental setup for study cryodestruction by using applicators based on sapphire shaped crystals with internal channels for optical irradiation of biotissues and detection of backscattered light. Due to the unique physical properties of sapphire, i.e. high thermal, mechanical, and chemical strength, high thermal conductivity and optical transparency, the sapphire cryoapplicators yield combination of the tissue cryodestruction with the optical control of tissue freezing. We have shown experimentally that using the proposed concept of applicator with several channels, it is possible to monitor changes of the ice ball during the cryodestruction process.

Original languageEnglish
Title of host publicationBiophotonics
Subtitle of host publicationPhotonic Solutions for Better Health Care VI
EditorsJurgen Popp, Valery V. Tuchin, Francesco Saverio Pavone
Number of pages7
ISBN (Electronic)9781510618961
DOIs
Publication statusPublished - Apr 2018
EventBiophotonics: Photonic Solutions for Better Health Care VI 2018 - Strasbourg, France
Duration: 23 Apr 201826 Apr 2018

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume10685
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceBiophotonics: Photonic Solutions for Better Health Care VI 2018
Country/TerritoryFrance
CityStrasbourg
Period23/04/1826/04/18

Keywords

  • cryodestruction
  • cryosurgery
  • ice ball control
  • Sapphire shaped crystals
  • spatially-resolved elastic light backscattering

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