Abnormality of mismatch negativity in response to tone omission in dyslexic adults

Alison E. Fisher*, Gareth R. Barnes, Arjan Hillebrand, Ian E. Holliday, Caroline Witton, Ian L. Richards

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Evidence of abnormalities in the perception of rapidly presented sounds in dyslexia has been interpreted as evidence of a prolonged time window within which sounds can influence the perception of temporally surrounding sounds. We recorded the magnetic mismatch negativity (MMNm) to infrequent tone omissions in a group of six dyslexic adults and six IQ and age-matched controls. An MMNm is only elicited in response to a complete stimulus omission when successive inputs fall within the temporal window of integration (stimulus onset asynchrony (SOA) ∼160 ms). No MMNm responses were recorded in either experimental group when stimuli were presented at SOAs falling just outside the temporal window of integration (SOA = 175 ms). However, while presentation rates of 100 ms resulted in MMNm responses for all control participants, the same stimulus omissions elicited an MMNm response in only one of the six dyslexic participants. These results cannot support the hypothesis of a prolonged time window of integration, but rather indicate auditory grouping deficits in the dyslexic population. © 2006 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)90-98
Number of pages9
JournalBrain Research
Volume1077
Issue number1
Early online date20 Feb 2006
DOIs
Publication statusPublished - 10 Mar 2006

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Dyslexia
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Keywords

  • dyslexia
  • magnetoencephalography
  • mismatch negativity
  • temporal window of integration

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Fisher, A. E., Barnes, G. R., Hillebrand, A., Holliday, I. E., Witton, C., & Richards, I. L. (2006). Abnormality of mismatch negativity in response to tone omission in dyslexic adults. Brain Research, 1077(1), 90-98. https://doi.org/10.1016/j.brainres.2005.12.121
Fisher, Alison E. ; Barnes, Gareth R. ; Hillebrand, Arjan ; Holliday, Ian E. ; Witton, Caroline ; Richards, Ian L. / Abnormality of mismatch negativity in response to tone omission in dyslexic adults. In: Brain Research. 2006 ; Vol. 1077, No. 1. pp. 90-98.
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Fisher, AE, Barnes, GR, Hillebrand, A, Holliday, IE, Witton, C & Richards, IL 2006, 'Abnormality of mismatch negativity in response to tone omission in dyslexic adults', Brain Research, vol. 1077, no. 1, pp. 90-98. https://doi.org/10.1016/j.brainres.2005.12.121

Abnormality of mismatch negativity in response to tone omission in dyslexic adults. / Fisher, Alison E.; Barnes, Gareth R.; Hillebrand, Arjan; Holliday, Ian E.; Witton, Caroline; Richards, Ian L.

In: Brain Research, Vol. 1077, No. 1, 10.03.2006, p. 90-98.

Research output: Contribution to journalArticle

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