A series of fluorescently labelled phytochelatin-like peptide sequences has been designed and synthesised as molecules with the ability both to bind to arsenite and to report this binding event. The peptides have been evaluated against a panel of biologically significant ions. The results of these initial studies are reported herein, and a structure which displays selectivity for As(III) over As(V) and other anions has been identified.
|Number of pages||3|
|Journal||Bioorganic and Medicinal Chemistry Letters|
|Publication status||Published - 10 Oct 2005|
- Peptide sensor