Development of a microbicide-releasing diaphragm as an HIV prevention strategy

Ian Major; Deborah Lowry; Karl Malcolm; David Woolfson; Jessica Cohen; Paul LaBarre; Maggie Kilbourne-Brook; Gene Saxon; David Friend

doi:10.1109/IEMBS.2010.5627333

Development of a microbicide-releasing diaphragm as an HIV prevention strategy

Ian Major, Deborah Lowry, Karl Malcolm, David Woolfson, Jessica Cohen, Paul LaBarre, Maggie Kilbourne-Brook, Gene Saxon, David Friend

Research output: Chapter in Book/Published conference output › Conference publication

Abstract

Contraceptive diaphragms offer a discreet method of pregnancy protection that women can use when needed with no side effects. Incorporating antiretroviral HIV microbicides into such devices may also provide protection against HIV infection. The paper gives a brief outline of the work being conducted by PATH, CONRAD and QUB on the development of a microbicide-releasing SILCS diaphragm. The design, engineering and manufacturing challenges that have been encountered will be discussed, as well as the potential impact such a device could have in the developing world.

Original language	English
Title of host publication	Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2010
Editors	I. Major
Publisher	IEEE
Pages	1089-1092
Number of pages	4
Volume	2010
DOIs	https://doi.org/10.1109/IEMBS.2010.5627333
Publication status	Published - 2010
Event	Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Buenos Aires, Argentina Duration: 31 Aug 2010 → 4 Sept 2010

Conference

Conference	Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Country/Territory	Argentina
City	Buenos Aires
Period	31/08/10 → 4/09/10

Keywords

Anti-HIV Agents
Anti-Infective Agents, Local
Contraceptive Devices, Female
Drug Implants
Equipment Design
Equipment Failure Analysis
Female
HIV Infections
Humans
Reproducibility of Results
Sensitivity and Specificity

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10.1109/IEMBS.2010.5627333

Cite this

Major, I., Lowry, D., Malcolm, K., Woolfson, D., Cohen, J., LaBarre, P., Kilbourne-Brook, M., Saxon, G., & Friend, D. (2010). Development of a microbicide-releasing diaphragm as an HIV prevention strategy. In I. Major (Ed.), Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2010 (Vol. 2010, pp. 1089-1092). IEEE. https://doi.org/10.1109/IEMBS.2010.5627333

@inproceedings{a1bc387970fe48158ca78ad684c23833,

title = "Development of a microbicide-releasing diaphragm as an HIV prevention strategy",

abstract = "Contraceptive diaphragms offer a discreet method of pregnancy protection that women can use when needed with no side effects. Incorporating antiretroviral HIV microbicides into such devices may also provide protection against HIV infection. The paper gives a brief outline of the work being conducted by PATH, CONRAD and QUB on the development of a microbicide-releasing SILCS diaphragm. The design, engineering and manufacturing challenges that have been encountered will be discussed, as well as the potential impact such a device could have in the developing world.",

keywords = "Anti-HIV Agents, Anti-Infective Agents, Local, Contraceptive Devices, Female, Drug Implants, Equipment Design, Equipment Failure Analysis, Female, HIV Infections, Humans, Reproducibility of Results, Sensitivity and Specificity",

author = "Ian Major and Deborah Lowry and Karl Malcolm and David Woolfson and Jessica Cohen and Paul LaBarre and Maggie Kilbourne-Brook and Gene Saxon and David Friend",

year = "2010",

doi = "10.1109/IEMBS.2010.5627333",

language = "English",

volume = "2010",

pages = "1089--1092",

editor = "I. Major",

booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2010",

publisher = "IEEE",

address = "United States",

note = "Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) ; Conference date: 31-08-2010 Through 04-09-2010",

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Major, I, Lowry, D, Malcolm, K, Woolfson, D, Cohen, J, LaBarre, P, Kilbourne-Brook, M, Saxon, G & Friend, D 2010, Development of a microbicide-releasing diaphragm as an HIV prevention strategy. in I Major (ed.), Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2010. vol. 2010, IEEE, pp. 1089-1092, Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Buenos Aires, Argentina, 31/08/10. https://doi.org/10.1109/IEMBS.2010.5627333

Development of a microbicide-releasing diaphragm as an HIV prevention strategy. / Major, Ian; Lowry, Deborah; Malcolm, Karl et al.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2010. ed. / I. Major. Vol. 2010 IEEE, 2010. p. 1089-1092.

Research output: Chapter in Book/Published conference output › Conference publication

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T1 - Development of a microbicide-releasing diaphragm as an HIV prevention strategy

AU - Major, Ian

AU - Lowry, Deborah

AU - Malcolm, Karl

AU - Woolfson, David

AU - Cohen, Jessica

AU - LaBarre, Paul

AU - Kilbourne-Brook, Maggie

AU - Saxon, Gene

AU - Friend, David

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AB - Contraceptive diaphragms offer a discreet method of pregnancy protection that women can use when needed with no side effects. Incorporating antiretroviral HIV microbicides into such devices may also provide protection against HIV infection. The paper gives a brief outline of the work being conducted by PATH, CONRAD and QUB on the development of a microbicide-releasing SILCS diaphragm. The design, engineering and manufacturing challenges that have been encountered will be discussed, as well as the potential impact such a device could have in the developing world.

KW - Anti-HIV Agents

KW - Anti-Infective Agents, Local

KW - Contraceptive Devices, Female

KW - Drug Implants

KW - Equipment Design

KW - Equipment Failure Analysis

KW - Female

KW - HIV Infections

KW - Humans

KW - Reproducibility of Results

KW - Sensitivity and Specificity

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BT - Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2010

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ER -

Development of a microbicide-releasing diaphragm as an HIV prevention strategy

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