DPP6 gene disruption in a family with Gilles de la Tourette syndrome

Keyphrases

• Gilles De La Tourette Syndrome 100%
• Gene Disruption 100%
• DPP6 100%
• Tourette Syndrome 83%
• Autism Spectrum Disorder 33%
• Paternal Uncle 33%
• Significant Level 16%
• Familial Cases 16%
• High-resolution 16%
• PCR Analysis 16%
• MRNA Level 16%
• Messenger RNA (mRNA) 16%
• Central Nervous System 16%
• Quantitative PCR 16%
• Duplication 16%
• Heritability 16%
• Tolerability 16%
• Large Cohort 16%
• Proband 16%
• Membrane Glycoproteins 16%
• Neurodevelopmental Disorders 16%
• Haloperidol 16%
• Psychiatric Comorbidity 16%
• Phonic Tic 16%
• Motor Tics 16%
• Multiple Motors 16%
• Molecular Link 16%
• Exonic 16%
• Microdeletion 16%
• Haploinsufficiency 16%
• SNP Array Analysis 16%
• Uncertain Significance 16%
• Array Comparative Genomic Hybridization (aCGH) 16%
• RT-quantitative PCR 16%
• Dyskinesia 16%
• Italian Families 16%
• First Exons 16%
• Fluorescence in Situ Hybridization 16%
• Genetic Architecture 16%

Biochemistry, Genetics and Molecular Biology

• Gene Targeting 100%
• Gene Disruption 100%
• DPP6 100%
• Membrane Protein 16%
• Messenger RNA 16%
• Downregulation 16%
• Quantitative Reverse Transcription Polymerase Chain Reaction 16%
• Real-Time Polymerase Chain Reaction 16%
• Proband 16%
• Comorbidity 16%
• Exon 16%
• Fluorescence in Situ Hybridization 16%
• Haloperidol 16%
• Array Comparative Genomic Hybridization 16%
• Dopamine Antagonist 16%
• Genetic Architecture 16%
• Haploinsufficiency 16%
• SNP Array 16%

Neuroscience

• Tourette Syndrome 100%
• Gene Disruption 100%
• Pervasive Developmental Disorder 28%
• Real-Time Polymerase Chain Reaction 28%
• Messenger RNA 14%
• Central Nervous System 14%
• Glycoprotein 14%
• In Situ Hybridization 14%
• Haloperidol 14%
• Neurodevelopmental Disorder 14%
• Dyskinesia 14%
• Psychiatric Co-Morbidity 14%
• Dopamine Antagonist 14%
• Haploinsufficiency 14%
• Exon 14%