TY - JOUR
T1 - Factors associated with the development of paediatric chronic otitis media by age nine
T2 - A prospective longitudinal cohort study of 6560 children
AU - Clamp, Philip
AU - De-Loyde, Katie
AU - Maw, Richard
AU - Gregory, Steven
AU - Golding, Jean
AU - Hall, Amanda
PY - 2020/11/19
Y1 - 2020/11/19
N2 - OBJECTIVE: This study aimed to analyse social, health and environmental factors associated with the development of chronic otitis media by age nine.METHOD: This was a prospective, longitudinal, birth cohort study of 6560 children, reviewed at age nine. Chronic otitis media defined as previous surgical history or video-otoscopic changes of tympanic membrane retraction, perforation or cholesteatoma. Non-affected children were used as the control group.RESULTS: Univariate analysis demonstrated an association between chronic otitis media and otorrhoea, snoring, grommet insertion, adenoidectomy, tonsillectomy, hearing loss, abnormal tympanograms and preterm birth. Multivariate analysis suggests many of these factors may be interrelated.CONCLUSION: The association between chronic otitis media and otorrhoea, abnormal tympanograms and grommets supports the role of the Eustachian tube and otitis media (with effusion or acute) in the pathogenesis of chronic otitis media. The role of snoring, adenoidectomy and tonsillectomy is unclear. Associations suggested by previous studies (sex, socioeconomic group, parental smoking, maternal education, childcare, crowding and siblings) were not found to be significant predictors in this analysis.
AB - OBJECTIVE: This study aimed to analyse social, health and environmental factors associated with the development of chronic otitis media by age nine.METHOD: This was a prospective, longitudinal, birth cohort study of 6560 children, reviewed at age nine. Chronic otitis media defined as previous surgical history or video-otoscopic changes of tympanic membrane retraction, perforation or cholesteatoma. Non-affected children were used as the control group.RESULTS: Univariate analysis demonstrated an association between chronic otitis media and otorrhoea, snoring, grommet insertion, adenoidectomy, tonsillectomy, hearing loss, abnormal tympanograms and preterm birth. Multivariate analysis suggests many of these factors may be interrelated.CONCLUSION: The association between chronic otitis media and otorrhoea, abnormal tympanograms and grommets supports the role of the Eustachian tube and otitis media (with effusion or acute) in the pathogenesis of chronic otitis media. The role of snoring, adenoidectomy and tonsillectomy is unclear. Associations suggested by previous studies (sex, socioeconomic group, parental smoking, maternal education, childcare, crowding and siblings) were not found to be significant predictors in this analysis.
KW - Adenoidectomy
KW - Cholesteatoma
KW - Cohort Studies
KW - Hearing Loss
KW - Middle Ear Ventilation
KW - Otitis Media
KW - Otological Surgical Procedures
KW - Pediatrics
KW - Risk Factors
KW - Snoring
KW - Tonsillectomy
KW - Tympanic Membrane Perforation
UR - http://www.scopus.com/inward/record.url?scp=85096548271&partnerID=8YFLogxK
UR - https://www.cambridge.org/core/journals/journal-of-laryngology-and-otology/article/abs/factors-associated-with-the-development-of-paediatric-chronic-otitis-media-by-age-nine-a-prospective-longitudinal-cohort-study-of-6560-children/A043F0FBD526C101B0D9899A325563F9
U2 - 10.1017/S0022215120002182
DO - 10.1017/S0022215120002182
M3 - Article
C2 - 33208197
AN - SCOPUS:85096548271
SN - 0022-2151
VL - 134
SP - 998
EP - 1009
JO - Journal of Laryngology and Otology
JF - Journal of Laryngology and Otology
IS - 11
ER -