Factors associated with the development of paediatric chronic otitis media by age nine: A prospective longitudinal cohort study of 6560 children

Philip Clamp*, Katie De-Loyde, Richard Maw, Steven Gregory, Jean Golding, Amanda Hall

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: This study aimed to analyse social, health and environmental factors associated with the development of chronic otitis media by age nine.

METHOD: This was a prospective, longitudinal, birth cohort study of 6560 children, reviewed at age nine. Chronic otitis media defined as previous surgical history or video-otoscopic changes of tympanic membrane retraction, perforation or cholesteatoma. Non-affected children were used as the control group.

RESULTS: Univariate analysis demonstrated an association between chronic otitis media and otorrhoea, snoring, grommet insertion, adenoidectomy, tonsillectomy, hearing loss, abnormal tympanograms and preterm birth. Multivariate analysis suggests many of these factors may be interrelated.

CONCLUSION: The association between chronic otitis media and otorrhoea, abnormal tympanograms and grommets supports the role of the Eustachian tube and otitis media (with effusion or acute) in the pathogenesis of chronic otitis media. The role of snoring, adenoidectomy and tonsillectomy is unclear. Associations suggested by previous studies (sex, socioeconomic group, parental smoking, maternal education, childcare, crowding and siblings) were not found to be significant predictors in this analysis.

Original languageEnglish
Number of pages12
JournalJournal of Laryngology and Otology
Early online date19 Nov 2020
DOIs
Publication statusE-pub ahead of print - 19 Nov 2020

Keywords

  • Adenoidectomy
  • Cholesteatoma
  • Cohort Studies
  • Hearing Loss
  • Middle Ear Ventilation
  • Otitis Media
  • Otological Surgical Procedures
  • Pediatrics
  • Risk Factors
  • Snoring
  • Tonsillectomy
  • Tympanic Membrane Perforation

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