Abstract
OBJECTIVE: To review the effectiveness data on the use of gabapentin in bipolar disorders.
DATA SOURCES: Clinical literature was accessed through MEDLINE (January 1985–November 2000). Key search terms included gabapentin, mood stabilizer, and bipolar disorder.
DATA SYNTHESIS: Bipolar disorder is a complex condition that can be difficult to treat effectively. Mood stabilizers are increasingly being used to manage bipolar disorder. Studies that used gabapentin in bipolar disorders are evaluated.
CONCLUSIONS: From the data presented, gabapentin cannot be recommended for treatment of bipolar disorder. Further studies are required to determine whether gabapentin has any role in the management of bipolar disorder.
DATA SOURCES: Clinical literature was accessed through MEDLINE (January 1985–November 2000). Key search terms included gabapentin, mood stabilizer, and bipolar disorder.
DATA SYNTHESIS: Bipolar disorder is a complex condition that can be difficult to treat effectively. Mood stabilizers are increasingly being used to manage bipolar disorder. Studies that used gabapentin in bipolar disorders are evaluated.
CONCLUSIONS: From the data presented, gabapentin cannot be recommended for treatment of bipolar disorder. Further studies are required to determine whether gabapentin has any role in the management of bipolar disorder.
| Original language | English |
|---|---|
| Pages (from-to) | 1264-1269 |
| Number of pages | 6 |
| Journal | Annals of Pharmacotherapy |
| Volume | 35 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 2001 |
Keywords
- acetic acids
- amines
- antimanic agents
- bipolar disorder
- cyclohexanecarboxylic acids
- humans
- randomized controlled trials as topic
- treatment outcome
- gamma-aminobutyric acid