In vivo fluorescence measurements of biological tissue viability

Viktor Dremin*, Sergei Sokolovski, Edik Rafailov, Elena Zharkikh, Elena Potapova, Andrey Dunaev, Evgenii Zherebtsov

*Corresponding author for this work

Research output: Chapter in Book/Published conference outputChapter


Modern preclinical and clinical studies show that the use of diagnostic methods based on the registration of fluorescent radiation can improve the early diagnosis of cancer and other destructive processes of various organs. Currently, many studies are being conducted aimed at studying the processes of oxidative metabolism using methods that register the fluorescence of various fluorophores. New instrument designs and analytical tools for the analysis of diagnostic information are being intensively developed. This chapter provides an overview of the main problems of fluorescence detection methods, experimental studies aimed at studying the effect of the main absorbing tissue chromophores on the fluorescence intensity, examples of applications in various fields of medicine and test objects for device calibration and measurement verification. This chapter does not seek to review all the existing problems of the method and present all possible areas of application, but only focuses on a number of important aspects.
Original languageEnglish
Title of host publicationAdvanced Photonics Methods for Biomedical Applications
EditorsEdik Rafailov, Tatjana Gric
Place of PublicationBoca Raton
PublisherCRC Press
Number of pages37
ISBN (Electronic)9781003228950
ISBN (Print)9781032128429
Publication statusPublished - 31 Jul 2023


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