Abstract
This article traces the roots of the antihyperglycaemic biguanide metformin from the use of Galega officinalis (goat's rue or French lilac) as a herbal treatment for the symptoms of diabetes. G. officinalis was found to be rich in guanidine, as a substance with blood glucose-lowering activity that formed the chemical basis of metformin. This insulin sensitising drug was introduced in 1957.
Original language | English |
---|---|
Pages (from-to) | 115-117 |
Number of pages | 3 |
Journal | Practical Diabetes International |
Volume | 21 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Apr 2004 |
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Keywords
- antidiabetic
- Galega officinalis
- metformin
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Metformin : its botanical background. / Bailey, C.J.; Day, C.
In: Practical Diabetes International, Vol. 21, No. 3, 01.04.2004, p. 115-117.Research output: Contribution to journal › Article
TY - JOUR
T1 - Metformin
T2 - its botanical background
AU - Bailey, C.J.
AU - Day, C.
PY - 2004/4/1
Y1 - 2004/4/1
N2 - This article traces the roots of the antihyperglycaemic biguanide metformin from the use of Galega officinalis (goat's rue or French lilac) as a herbal treatment for the symptoms of diabetes. G. officinalis was found to be rich in guanidine, as a substance with blood glucose-lowering activity that formed the chemical basis of metformin. This insulin sensitising drug was introduced in 1957.
AB - This article traces the roots of the antihyperglycaemic biguanide metformin from the use of Galega officinalis (goat's rue or French lilac) as a herbal treatment for the symptoms of diabetes. G. officinalis was found to be rich in guanidine, as a substance with blood glucose-lowering activity that formed the chemical basis of metformin. This insulin sensitising drug was introduced in 1957.
KW - antidiabetic
KW - Galega officinalis
KW - metformin
UR - http://onlinelibrary.wiley.com/doi/10.1002/pdi.606/abstract
UR - http://www.scopus.com/inward/record.url?scp=2342424434&partnerID=8YFLogxK
U2 - 10.1002/pdi.606
DO - 10.1002/pdi.606
M3 - Article
AN - SCOPUS:2342424434
VL - 21
SP - 115
EP - 117
JO - Practical Diabetes International
JF - Practical Diabetes International
SN - 1357-8170
IS - 3
ER -