Metformin: its botanical background

C.J. Bailey; C. Day

doi:10.1002/pdi.606

Metformin: its botanical background

C.J. Bailey^*, C. Day

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

This article traces the roots of the antihyperglycaemic biguanide metformin from the use of Galega officinalis (goat's rue or French lilac) as a herbal treatment for the symptoms of diabetes. G. officinalis was found to be rich in guanidine, as a substance with blood glucose-lowering activity that formed the chemical basis of metformin. This insulin sensitising drug was introduced in 1957.

Original language	English
Pages (from-to)	115-117
Number of pages	3
Journal	Practical Diabetes International
Volume	21
Issue number	3
DOIs	https://doi.org/10.1002/pdi.606
Publication status	Published - 1 Apr 2004

Keywords

antidiabetic
Galega officinalis
metformin

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10.1002/pdi.606

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AB - This article traces the roots of the antihyperglycaemic biguanide metformin from the use of Galega officinalis (goat's rue or French lilac) as a herbal treatment for the symptoms of diabetes. G. officinalis was found to be rich in guanidine, as a substance with blood glucose-lowering activity that formed the chemical basis of metformin. This insulin sensitising drug was introduced in 1957.

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Metformin: its botanical background

Abstract

Keywords

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