Modeling of Evolving RNA Replicators

Jacobo Aguirre, Michael Stich

Research output: Chapter in Book/Published conference outputOther chapter contribution


Populations of RNA replicators are a conceptually simple model to study evolutionary processes. Their prime applications comprise molecular evolution such as observed in viral populations, SELEX experiments, or the study of the origin and early evolution of life. Nevertheless, due to their simplicity compared to living organisms, they represent a paradigmatic model for Darwinian evolution as such. In this chapter, we review some properties of RNA populations in evolution, and focus on the structure of the underlying neutral networks, intimately related to the sequence-structure map for RNA molecules.
Original languageEnglish
Title of host publicationNonlinear Dynamics in Biological Systems
EditorsJorge Carballido-Landeira, Bruno Escribano
ISBN (Electronic)978-3-319-33054-9
Publication statusPublished - 21 Jul 2016

Publication series

NameNonlinear Dynamics in Biological Systems
ISSN (Print)2199-3041
ISSN (Electronic)2199-305X


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