Modeling of Evolving RNA Replicators

Jacobo Aguirre, Michael Stich

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

Abstract

Populations of RNA replicators are a conceptually simple model to study evolutionary processes. Their prime applications comprise molecular evolution such as observed in viral populations, SELEX experiments, or the study of the origin and early evolution of life. Nevertheless, due to their simplicity compared to living organisms, they represent a paradigmatic model for Darwinian evolution as such. In this chapter, we review some properties of RNA populations in evolution, and focus on the structure of the underlying neutral networks, intimately related to the sequence-structure map for RNA molecules.
Original languageEnglish
Title of host publicationNonlinear Dynamics in Biological Systems
EditorsJorge Carballido-Landeira, Bruno Escribano
Pages1-18
Volume7
ISBN (Electronic)978-3-319-33054-9
DOIs
Publication statusPublished - 21 Jul 2016

Publication series

NameNonlinear Dynamics in Biological Systems
Volume7
ISSN (Print)2199-3041
ISSN (Electronic)2199-305X

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Modeling
Neutral Networks
Molecular Evolution
Simplicity
Molecules
Model
Experiment
Review
Life

Cite this

Aguirre, J., & Stich, M. (2016). Modeling of Evolving RNA Replicators. In J. Carballido-Landeira, & B. Escribano (Eds.), Nonlinear Dynamics in Biological Systems (Vol. 7, pp. 1-18). [Chapter 1] (Nonlinear Dynamics in Biological Systems; Vol. 7). https://doi.org/10.1007/978-3-319-33054-9_1
Aguirre, Jacobo ; Stich, Michael. / Modeling of Evolving RNA Replicators. Nonlinear Dynamics in Biological Systems. editor / Jorge Carballido-Landeira ; Bruno Escribano. Vol. 7 2016. pp. 1-18 (Nonlinear Dynamics in Biological Systems).
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Aguirre, J & Stich, M 2016, Modeling of Evolving RNA Replicators. in J Carballido-Landeira & B Escribano (eds), Nonlinear Dynamics in Biological Systems. vol. 7, Chapter 1, Nonlinear Dynamics in Biological Systems, vol. 7, pp. 1-18. https://doi.org/10.1007/978-3-319-33054-9_1

Modeling of Evolving RNA Replicators. / Aguirre, Jacobo; Stich, Michael.

Nonlinear Dynamics in Biological Systems. ed. / Jorge Carballido-Landeira; Bruno Escribano. Vol. 7 2016. p. 1-18 Chapter 1 (Nonlinear Dynamics in Biological Systems; Vol. 7).

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

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Aguirre J, Stich M. Modeling of Evolving RNA Replicators. In Carballido-Landeira J, Escribano B, editors, Nonlinear Dynamics in Biological Systems. Vol. 7. 2016. p. 1-18. Chapter 1. (Nonlinear Dynamics in Biological Systems). https://doi.org/10.1007/978-3-319-33054-9_1