Optical diagnostics of vascular reactions triggered by weak allergens using laser speckle-contrast imaging technique

Yu L. Kuznetsov*, V. V. Kalchenko, N. G. Astaf'eva, I. V. Meglinski

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

The capability of using the laser speckle contrast imaging technique with a long exposure time for visualisation of primary acute skin vascular reactions caused by a topical application of a weak contact allergen is considered. The method is shown to provide efficient and accurate detection of irritant-induced primary acute vascular reactions of skin. The presented technique possesses a high potential in everyday diagnostic practice, preclinical studies, as well as in the prognosis of skin reactions to the interaction with potentially allergenic materials.

Original languageEnglish
Pages (from-to)713-718
Number of pages6
JournalQuantum Electronics
Volume44
Issue number8
DOIs
Publication statusPublished - 1 Jan 2014

Keywords

  • Allergen
  • Contact irritant
  • Exposure time
  • Laser speckle contrast imaging
  • Skin
  • Vasculature

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