Reading on the right when there’s nothing left? Probabilistic tractography reveals hemispheric asymmetry in pure alexia

Michele Veldsman*, Tobias Loetscher, Amanda Wood, Amy Brodtmann

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

We present a patient with reading inexpertise and right hemianopia following left posterior cerebral artery (PCA) stroke. We examine the extent of disruption to reading performance and the extent of white matter tract damage relative to a patient with more limited PCA infarction and isolated right hemianopia. We show white matter disconnection of the temporal occipital fusiform cortex in our pure alexia patient. Connectivity-based laterality indices revealed right hemisphere laterality in the alexia patient; this was not associated with improved reading function. We speculate that the degree of premorbid laterality may be a critical factor affecting the extent of reading dysfunction in alexia.

Original languageEnglish
JournalNeurocase
Volumein press
DOIs
Publication statusPublished - 9 Aug 2017

Bibliographical note

This is an Accepted Manuscript of an article published by Taylor & Francis in Neurocase on 9/8/17, available online: http://www.tandfonline.com/10.1080/13554794.2017.1364775

Keywords

  • alexia
  • diffusion tractography
  • Reading
  • stroke

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