Schizophrenia spectrum disorders and autism spectrum disorder

Katharine Chisholm*, Ashleigh Lin, Marco Armando

*Corresponding author for this work

Research output: Chapter in Book/Published conference outputChapter


Schizophrenia spectrum disorders (SSD) and autism spectrum disorder (ASD) are currently conceptualised as separate illnesses; however, this has not always been the case. The disorders share multiple phenotypic similarities and risk factors and have been reported to co-occur at elevated rates. In this chapter, we examine the level of comorbidity found between the disorders and the overlap between ASD and SSD at a clinical and trait level and discuss difficulties in the diagnosis and evaluation of the disorders. We then discuss genetic and neurobiological evidence, highlighting similarities and areas of distinction. Finally, we present treatment options, including non-medical and novel treatment strategies as well as pharmacological interventions.
Original languageEnglish
Title of host publicationPsychiatric Symptoms and Comorbidities in Autism Spectrum Disorder
Number of pages16
ISBN (Electronic)9783319296951
ISBN (Print)9783319296937
Publication statusPublished - 19 May 2016


Dive into the research topics of 'Schizophrenia spectrum disorders and autism spectrum disorder'. Together they form a unique fingerprint.

Cite this