TY - JOUR
T1 - Speckle dynamics under ergodicity breaking
AU - Sdobnov, Anton
AU - Bykov, Alexander
AU - Molodij, Guillaume
AU - Kalchenko, Vyacheslav
AU - Jarvinen, Topias
AU - Popov, Alexey
AU - Kordas, Krisztian
AU - Meglinski, Igor
PY - 2018/3/26
Y1 - 2018/3/26
N2 - Laser speckle contrast imaging (LSCI) is a well-known and versatile approach for the non-invasive visualization of flows and microcirculation localized in turbid scattering media, including biological tissues. In most conventional implementations of LSCI the ergodic regime is typically assumed valid. However, most composite turbid scattering media, especially biological tissues, are non-ergodic, containing a mixture of dynamic and static centers of light scattering. In the current study, we examined the speckle contrast in different dynamic conditions with the aim of assessing limitations in the quantitative interpretation of speckle contrast images. Based on a simple phenomenological approach, we introduced a coefficient of speckle dynamics to quantitatively assess the ratio of the dynamic part of a scattering medium to the static one. The introduced coefficient allows one to distinguish real changes in motion from the mere appearance of static components in the field of view. As examples of systems with static/dynamic transitions, thawing and heating of Intralipid samples were studied by the LSCI approach.
AB - Laser speckle contrast imaging (LSCI) is a well-known and versatile approach for the non-invasive visualization of flows and microcirculation localized in turbid scattering media, including biological tissues. In most conventional implementations of LSCI the ergodic regime is typically assumed valid. However, most composite turbid scattering media, especially biological tissues, are non-ergodic, containing a mixture of dynamic and static centers of light scattering. In the current study, we examined the speckle contrast in different dynamic conditions with the aim of assessing limitations in the quantitative interpretation of speckle contrast images. Based on a simple phenomenological approach, we introduced a coefficient of speckle dynamics to quantitatively assess the ratio of the dynamic part of a scattering medium to the static one. The introduced coefficient allows one to distinguish real changes in motion from the mere appearance of static components in the field of view. As examples of systems with static/dynamic transitions, thawing and heating of Intralipid samples were studied by the LSCI approach.
KW - ergodicity
KW - motion estimation
KW - optical imaging
KW - speckle contrast
KW - speckle pattern
UR - http://www.scopus.com/inward/record.url?scp=85044841847&partnerID=8YFLogxK
UR - https://iopscience.iop.org/article/10.1088/1361-6463/aab404
U2 - 10.1088/1361-6463/aab404
DO - 10.1088/1361-6463/aab404
M3 - Article
AN - SCOPUS:85044841847
SN - 0022-3727
VL - 51
JO - Journal of Physics D: Applied Physics
JF - Journal of Physics D: Applied Physics
IS - 15
M1 - 155401
ER -