Synthesis of S6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its incorporation into oligoribonucleotides

Qinguo Zheng*, Yang Wang, Eric Lattmann

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The preparation of N2-phenoxylacetyl-S 6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its subsequent incorporation into oligoribonucleotides is described. The identity of the oligonucleotides was confirmed by UV spectrophotometry and nucleoside composition analysis. © 2003 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)3141-3144
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume13
Issue number19
DOIs
Publication statusPublished - 16 Oct 2003

Keywords

  • preparation
  • N2-phenoxylacetyl-S6-(2
  • 4-dinitrophenyl)-6-thioguanosine phosphoramidite
  • incorporation
  • oligoribonucleotides

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