Abstract
Aim: A causative relationship between acute coronary syndrome (ACS) and periodontitis has yet to be defined. The aim of this study was to assess differences in levels of serum cytokines between individuals with or without ACS or periodontal comorbidity. Material and Methods: In a case–control study, individuals with ACS (78 individuals, 10.3% females) and matching healthy controls (78 individuals, 28.2% females) were included. Medical and dental examinations were performed to diagnose ACS and periodontitis. Serum levels of cytokines were assessed, using Luminex technology. Results: A diagnosis of periodontitis in the ACS and control group was diagnosed in 52.6% and 12.8% of the individuals, respectively. The unadjusted odds-ratio that individuals with ACS also had periodontitis was 7.5 (95% CI: 3.4, 16.8, p
| Original language | English |
|---|---|
| Pages (from-to) | 713-719 |
| Number of pages | 7 |
| Journal | Journal of Clinical Periodontology |
| Volume | 43 |
| Issue number | 9 |
| Early online date | 2 Jul 2016 |
| DOIs | |
| Publication status | Published - Sep 2016 |
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Bibliographical note
This is the peer reviewed version of the following article: Widén, C., Holmer, H., Coleman, M., Tudor, M., Ohlsson, O., Sättlin, S., ... Persson, G. R. (2016). Systemic inflammatory impact of periodontitis on acute coronary syndrome. Journal of Clinical Periodontology, 43(9), 713-719, which has been published in final form at http://dx.doi.org/10.1111/jcpe.12540. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-ArchivingKeywords
- cardiovascular disease
- cytokines
- hs-CRP
- human
- oral disease
- serum
- VEGF
Cite this
}
Systemic inflammatory impact of periodontitis on acute coronary syndrome. / Widén, Cecilia; Holmer, Helene; Coleman, Michael; Tudor, Marian; Ohlsson, Ola; Sättlin, Susanna; Renvert, Stefan; Persson, Goesta Rutger.
In: Journal of Clinical Periodontology, Vol. 43, No. 9, 09.2016, p. 713-719.Research output: Contribution to journal › Article
TY - JOUR
T1 - Systemic inflammatory impact of periodontitis on acute coronary syndrome
AU - Widén, Cecilia
AU - Holmer, Helene
AU - Coleman, Michael
AU - Tudor, Marian
AU - Ohlsson, Ola
AU - Sättlin, Susanna
AU - Renvert, Stefan
AU - Persson, Goesta Rutger
N1 - This is the peer reviewed version of the following article: Widén, C., Holmer, H., Coleman, M., Tudor, M., Ohlsson, O., Sättlin, S., ... Persson, G. R. (2016). Systemic inflammatory impact of periodontitis on acute coronary syndrome. Journal of Clinical Periodontology, 43(9), 713-719, which has been published in final form at http://dx.doi.org/10.1111/jcpe.12540. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving
PY - 2016/9
Y1 - 2016/9
N2 - Aim: A causative relationship between acute coronary syndrome (ACS) and periodontitis has yet to be defined. The aim of this study was to assess differences in levels of serum cytokines between individuals with or without ACS or periodontal comorbidity. Material and Methods: In a case–control study, individuals with ACS (78 individuals, 10.3% females) and matching healthy controls (78 individuals, 28.2% females) were included. Medical and dental examinations were performed to diagnose ACS and periodontitis. Serum levels of cytokines were assessed, using Luminex technology. Results: A diagnosis of periodontitis in the ACS and control group was diagnosed in 52.6% and 12.8% of the individuals, respectively. The unadjusted odds-ratio that individuals with ACS also had periodontitis was 7.5 (95% CI: 3.4, 16.8, p
AB - Aim: A causative relationship between acute coronary syndrome (ACS) and periodontitis has yet to be defined. The aim of this study was to assess differences in levels of serum cytokines between individuals with or without ACS or periodontal comorbidity. Material and Methods: In a case–control study, individuals with ACS (78 individuals, 10.3% females) and matching healthy controls (78 individuals, 28.2% females) were included. Medical and dental examinations were performed to diagnose ACS and periodontitis. Serum levels of cytokines were assessed, using Luminex technology. Results: A diagnosis of periodontitis in the ACS and control group was diagnosed in 52.6% and 12.8% of the individuals, respectively. The unadjusted odds-ratio that individuals with ACS also had periodontitis was 7.5 (95% CI: 3.4, 16.8, p
KW - cardiovascular disease
KW - cytokines
KW - hs-CRP
KW - human
KW - oral disease
KW - serum
KW - VEGF
UR - http://www.scopus.com/inward/record.url?scp=84980605473&partnerID=8YFLogxK
U2 - 10.1111/jcpe.12540
DO - 10.1111/jcpe.12540
M3 - Article
C2 - 26935585
VL - 43
SP - 713
EP - 719
JO - Journal of Clinical Periodontology
JF - Journal of Clinical Periodontology
SN - 0303-6979
IS - 9
ER -