The design and validation of an optical coherence tomography-based classification system for focal vitreomacular traction

D.H.W. Steel, L. Downey, K. Greiner, H. Heimann, T.L. Jackson, Z. Koshy, D.A.H. Laidlaw, L. Wickham, Yang Yit

Research output: Contribution to journalArticle

Abstract

PurposeTo develop and validate a classification system for focal vitreomacular traction (VMT) with and without macular hole based on spectral domain optical coherence tomography (SD-OCT), intended to aid in decision-making and prognostication.MethodsA panel of retinal specialists convened to develop this system. A literature review followed by discussion on a wide range of cases formed the basis for the proposed classification. Key features on OCT were identified and analysed for their utility in clinical practice. A final classification was devised based on two sequential, independent validation exercises to improve interobserver variability.ResultsThis classification tool pertains to idiopathic focal VMT assessed by a horizontal line scan using SD-OCT. The system uses width (W), interface features (I), foveal shape (S), retinal pigment epithelial changes (P), elevation of vitreous attachment (E), and inner and outer retinal changes (R) to give the acronym WISPERR. Each category is scored hierarchically. Results from the second independent validation exercise indicated a high level of agreement between graders: intraclass correlation ranged from 0.84 to 0.99 for continuous variables and Fleiss' kappa values ranged from 0.76 to 0.95 for categorical variables.ConclusionsWe present an OCT-based classification system for focal VMT that allows anatomical detail to be scrutinised and scored qualitatively and quantitatively using a simple, pragmatic algorithm, which may be of value in clinical practice as well as in future research studies.

Original languageEnglish
Pages (from-to)314-324
Number of pages11
JournalEye
Volume30
Issue number2
Early online date15 Jan 2016
DOIs
Publication statusPublished - Feb 2016

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Optical Coherence Tomography
Traction
Retinal Perforations
Retinal Pigments
Observer Variation
Decision Making

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Steel, D. H. W., Downey, L., Greiner, K., Heimann, H., Jackson, T. L., Koshy, Z., ... Yit, Y. (2016). The design and validation of an optical coherence tomography-based classification system for focal vitreomacular traction. Eye, 30(2), 314-324. https://doi.org/10.1038/eye.2015.262
Steel, D.H.W. ; Downey, L. ; Greiner, K. ; Heimann, H. ; Jackson, T.L. ; Koshy, Z. ; Laidlaw, D.A.H. ; Wickham, L. ; Yit, Yang. / The design and validation of an optical coherence tomography-based classification system for focal vitreomacular traction. In: Eye. 2016 ; Vol. 30, No. 2. pp. 314-324.
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Steel, DHW, Downey, L, Greiner, K, Heimann, H, Jackson, TL, Koshy, Z, Laidlaw, DAH, Wickham, L & Yit, Y 2016, 'The design and validation of an optical coherence tomography-based classification system for focal vitreomacular traction', Eye, vol. 30, no. 2, pp. 314-324. https://doi.org/10.1038/eye.2015.262

The design and validation of an optical coherence tomography-based classification system for focal vitreomacular traction. / Steel, D.H.W.; Downey, L.; Greiner, K.; Heimann, H.; Jackson, T.L.; Koshy, Z.; Laidlaw, D.A.H.; Wickham, L.; Yit, Yang.

In: Eye, Vol. 30, No. 2, 02.2016, p. 314-324.

Research output: Contribution to journalArticle

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AU - Downey, L.

AU - Greiner, K.

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AU - Jackson, T.L.

AU - Koshy, Z.

AU - Laidlaw, D.A.H.

AU - Wickham, L.

AU - Yit, Yang

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