The development of the gut microbiome and temperament during infancy and early childhood: A systematic review.

Emma Alving-Jessep, Edith Botchway, Amanda Wood, Anthony Hilton, Jackie Blissett*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Temperament in early childhood is a good predictor of later personality, behavior, and risk of psychopathology. Variation in temperament can be explained by environmental and biological factors. One biological mechanism of interest is the gut microbiome (GM), which has been associated with mental and physical health. This review synthesized existing literature evaluating the relationship between GM composition and diversity, and temperament in early life. Web of Science, PsycInfo, PubMed, and Scopus were searched, and data were extracted according to PRISMA guidelines. In total, 1562 studies were identified, of which six remained following application of exclusion/inclusion criteria. The findings suggest that there is an association between higher alpha diversity and temperament: greater Surgency/Extraversion and High-Intensity Pleasure in males, and lower Effortful Control in females. Unique community structures (beta diversity) were found for Surgency/Extraversion in males and Fear in females. An emerging pattern of positive temperament traits being associated with GM communities biased toward short-chain fatty acid production from a metabolism based on dietary fiber and complex carbohydrates was observed and is worthy of further investigation. To gain deeper understanding of the relationship, future research should investigate further the functional aspects of the microbiome and the influence of diet.
Original languageEnglish
Article numbere22306
JournalDevelopmental Psychobiology
Volume64
Issue number7
Early online date13 Jul 2022
DOIs
Publication statusE-pub ahead of print - 13 Jul 2022

Bibliographical note

© 2022 The Authors. Developmental Psychobiology published by Wiley Periodicals LLC.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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