The effect of voluntary fasting and dehydration on flicker-induced retinal vascular dilation in a healthy individual: a case report

Rebekka Heitmar, Doina Gherghel, Richard A. Armstrong, Robert P Cubbidge, Sarah Hosking

Research output: Contribution to journalArticlepeer-review

Abstract

INTRODUCTION: Dynamic retinal vessel analysis represents a well-established method for the assessment of vascular reactivity during both normal conditions and after various provocations. We present a case where the subject showed abnormal retinal vessel reactivity after fasting voluntarily for 20 hours. CASE PRESENTATION: A healthy, 21-year-old man who fasted voluntarily for 20 hours exhibited abnormal retinal vascular reactivity (dilation and constriction) after flicker provocation as measured using the Dynamic Retinal Vessel Analyser (Imedos, Jena, Germany). CONCLUSION: The abnormal vascular reactivity induced by fasting was significant; abnormal levels of important nutrients due to fasting and dehydration could play a role through altering the concentration of vasoactive substances such as nitric oxide. This hypothesis needs further investigation.
Original languageEnglish
Article number153
Pages (from-to)1-7
Number of pages7
JournalJournal of Medical Case Reports
Volume2
Issue number153
DOIs
Publication statusPublished - 13 May 2008

Bibliographical note

© 2008 Heitmar et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords

  • dynamic retinal vessel analysis
  • assessment
  • vascular reactivity
  • abnormal retinal vessel reactivity
  • fasting

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